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    NR1H2 nuclear receptor subfamily 1 group H member 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 719210, updated on 17-Aug-2024

    Summary

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    Official Symbol
    NR1H2provided by VGNC
    Official Full Name
    nuclear receptor subfamily 1 group H member 2provided by VGNC
    Primary source
    VGNC:VGNC:75504
    Locus tag
    EGK_10924
    See related
    Ensembl:ENSMMUG00000023418
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See NR1H2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 19 NC_041772.1 (50283445..50290672)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 19 NC_027911.1 (45739406..45746610)

    Chromosome 19 - NC_041772.1Genomic Context describing neighboring genes Neighboring gene napsin-A Neighboring gene uncharacterized LOC114674080 Neighboring gene napsin-A Neighboring gene transcription factor Spi-B Neighboring gene myosin binding protein C2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    oxysterols receptor LXR-beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001194697.1 → NP_001181626.1  oxysterols receptor LXR-beta

      See identical proteins and their annotated locations for NP_001181626.1

      Status: PROVISIONAL

      Source sequence(s)
      QNVO02000236
      UniProtKB/TrEMBL
      A0A8J8XDQ9, F6ZNM1, F7F982, G7NLR5
      Related
      ENSMMUP00000030833.2, ENSMMUT00000032951.4
      Conserved Domains (2) summary
      cd06954
      Location:224 → 459
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:67 → 163
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041772.1 Reference Mmul_10 Primary Assembly

      Range
      50283445..50290672
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028838520.1 → XP_028694353.1  oxysterols receptor LXR-beta isoform X3

      Conserved Domains (1) summary
      cd06954
      Location:127 → 362
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors

    2. XM_015124414.2 → XP_014979900.1  oxysterols receptor LXR-beta isoform X2

      Conserved Domains (2) summary
      cd06954
      Location:144 → 379
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:1 → 83
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    3. XM_015124413.2 → XP_014979899.1  oxysterols receptor LXR-beta isoform X1

      UniProtKB/TrEMBL
      A0A8J8XDQ9, F6ZNM1, F7F982, G7NLR5
      Conserved Domains (2) summary
      cd06954
      Location:224 → 459
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
      cl02596
      Location:67 → 163
      NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

    4. XM_028838521.1 → XP_028694354.1  oxysterols receptor LXR-beta isoform X3

      Conserved Domains (1) summary
      cd06954
      Location:127 → 362
      NR_LBD_LXR; The ligand binding domain of Liver X receptors, a family of nuclear receptors of ligand-activated transcription factors
    Nucleotide Protein
    Heading Accession and Version

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