U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 [ Bos taurus (domestic cattle) ]

    Gene ID: 527762, updated on 30-Jan-2025

    Summary

    Go to the top of the page Help
    Official Symbol
    KCNE3provided by VGNC
    Official Full Name
    potassium voltage-gated channel subfamily E regulatory subunit 3provided by VGNC
    Primary source
    VGNC:VGNC:30438
    See related
    BGD:BT27500; EnsemblRapid:ENSBTAG00070034172
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See KCNE3 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (53807201..53821245, complement)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene phosphoglucomutase 2 like 1 Neighboring gene U6 spliceosomal RNA Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene uncharacterized LOC132342343 Neighboring gene lipoyl(octanoyl) transferase 2 Neighboring gene DNA polymerase delta 3, accessory subunit

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables delayed rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables potassium channel regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane transporter binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in membrane repolarization during action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of delayed rectifier potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in potassium ion export across plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of heart rate by cardiac conduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of ventricular cardiac muscle cell membrane repolarization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ventricular cardiac muscle cell action potential IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    potassium voltage-gated channel subfamily E member 3
    Names
    potassium voltage-gated channel, Isk-related family, member 3

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001435391.1 → NP_001422320.1  potassium voltage-gated channel subfamily E member 3

      Status: VALIDATED

      Source sequence(s)
      NKLS02000015
      Related
      ENSBTAP00070046887.1, ENSBTAT00070076987.1

    2. NM_001435392.1 → NP_001422321.1  potassium voltage-gated channel subfamily E member 3

      Status: VALIDATED

      Source sequence(s)
      NKLS02000015
      Related
      ENSBTAP00070046871.1, ENSBTAT00070076963.1

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      53807201..53821245 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024975878.2 → XP_024831646.2  potassium voltage-gated channel subfamily E member 3 isoform X4

    2. XM_024975875.2 → XP_024831643.1  potassium voltage-gated channel subfamily E member 3 isoform X3

    3. XM_024975873.2 → XP_024831641.1  potassium voltage-gated channel subfamily E member 3 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S0G3
      Conserved Domains (1) summary
      pfam02060
      Location:44 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    4. XM_005200956.5 → XP_005201013.1  potassium voltage-gated channel subfamily E member 3 isoform X1

      See identical proteins and their annotated locations for XP_005201013.1

      UniProtKB/TrEMBL
      A0AAA9S0G3
      Related
      ENSBTAP00070046880.1, ENSBTAT00070076976.1
      Conserved Domains (1) summary
      pfam02060
      Location:44 → 92
      ISK_Channel; Slow voltage-gated potassium channel

    5. XM_059875131.1 → XP_059731114.1  potassium voltage-gated channel subfamily E member 3 isoform X1

      UniProtKB/TrEMBL
      A0AAA9S0G3
      Related
      ENSBTAP00070046826.1, ENSBTAT00070076903.1

    6. XM_024975874.2 → XP_024831642.1  potassium voltage-gated channel subfamily E member 3 isoform X2

    7. XM_024975876.2 → XP_024831644.1  potassium voltage-gated channel subfamily E member 3 isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials