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    TAF1 TATA-box binding protein associated factor 1 [ Equus caballus (horse) ]

    Gene ID: 100056106, updated on 19-Dec-2024

    Summary

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    Gene symbol
    TAF1
    Gene description
    TATA-box binding protein associated factor 1
    See related
    Ensembl:ENSECAG00000006365
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Equus caballus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
    Orthologs
    human mouse all
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    Genomic context

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    See TAF1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    RS_2024_12 current TB-T2T (GCF_041296265.1) X NC_091715.1 (67846755..67918472)
    RS_2024_08 previous assembly EquCab3.0 (GCF_002863925.1) X NC_009175.3 (56272345..56343811)

    Chromosome X - NC_091715.1Genomic Context describing neighboring genes Neighboring gene integrin subunit beta 1 binding protein 2 Neighboring gene RHOG family member 2 Neighboring gene pleckstrin homology domain-containing family B member 2 pseudogene Neighboring gene suppressor of cytokine signaling 6-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Thoroughbred Stallion gene expression
    • BioProject: PRJEB53382
    • Analysis date: Mon Jan 06 09:53:19 2025

    Bibliography

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    Related articles in PubMed

    1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II general transcription initiation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II general transcription initiation factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables TBP-class protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables histone acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA-templated transcription initiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in RNA polymerase II preinitiation complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription initiation factor TFIID subunit 1
    Names
    TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_041296265.1-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference TB-T2T Primary Assembly

    Genomic

    1. NC_091715.1 Reference TB-T2T Primary Assembly

      Range
      67846755..67918472
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005614257.4 → XP_005614314.1  transcription initiation factor TFIID subunit 1 isoform X1

      UniProtKB/TrEMBL
      F7DCA8, F7DCN3
      Related
      ENSECAP00000005777.3
      Conserved Domains (6) summary
      cd05511
      Location:1528 → 1640
      Bromo_TFIID; Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to ...
      PHA02664
      Location:1698 → 1811
      PHA02664; hypothetical protein; Provisional
      pfam09247
      Location:33 → 86
      TBP-binding; TATA box-binding protein binding
      pfam12157
      Location:586 → 1048
      DUF3591; Protein of unknown function (DUF3591)
      pfam14797
      Location:1774 → 1865
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      pfam15288
      Location:1282 → 1317
      zf-CCHC_6; Zinc knuckle

    2. XM_003365809.5 → XP_003365857.1  transcription initiation factor TFIID subunit 1 isoform X5

      UniProtKB/TrEMBL
      F7DCA8
      Related
      ENSECAP00000060325.1
      Conserved Domains (5) summary
      cd05511
      Location:1528 → 1640
      Bromo_TFIID; Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to ...
      pfam09247
      Location:33 → 86
      TBP-binding; TATA box-binding protein binding
      pfam12157
      Location:586 → 1048
      DUF3591; Protein of unknown function (DUF3591)
      pfam14797
      Location:1740 → 1831
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      pfam15288
      Location:1282 → 1317
      zf-CCHC_6; Zinc knuckle

    3. XM_070258793.1 → XP_070114894.1  transcription initiation factor TFIID subunit 1 isoform X2

    4. XM_070258797.1 → XP_070114898.1  transcription initiation factor TFIID subunit 1 isoform X6

    5. XM_070258794.1 → XP_070114895.1  transcription initiation factor TFIID subunit 1 isoform X3

    6. XM_001493192.7 → XP_001493242.2  transcription initiation factor TFIID subunit 1 isoform X7

      UniProtKB/TrEMBL
      F7DCA8
      Conserved Domains (5) summary
      cd05511
      Location:1507 → 1619
      Bromo_TFIID; Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to ...
      pfam09247
      Location:33 → 86
      TBP-binding; TATA box-binding protein binding
      pfam12157
      Location:565 → 1027
      DUF3591; Protein of unknown function (DUF3591)
      pfam14797
      Location:1719 → 1810
      SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
      pfam15288
      Location:1261 → 1296
      zf-CCHC_6; Zinc knuckle

    7. XM_070258795.1 → XP_070114896.1  transcription initiation factor TFIID subunit 1 isoform X4

    8. XM_070258798.1 → XP_070114899.1  transcription initiation factor TFIID subunit 1 isoform X8

    9. XM_070258799.1 → XP_070114900.1  transcription initiation factor TFIID subunit 1 isoform X9

    Nucleotide Protein
    Heading Accession and Version

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