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    Vsig1 V-set and immunoglobulin domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 78789, updated on 27-Nov-2024

    Summary

    Official Symbol
    Vsig1provided by MGI
    Official Full Name
    V-set and immunoglobulin domain containing 1provided by MGI
    Primary source
    MGI:MGI:1926039
    See related
    Ensembl:ENSMUSG00000031430 AllianceGenome:MGI:1926039
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700062D20Rik; 4930405J24Rik
    Summary
    Acts upstream of or within epithelial cell morphogenesis and maintenance of gastrointestinal epithelium. Located in basolateral plasma membrane. Is expressed in ovary; stomach; stomach glandular epithelium; stomach glandular region epithelium; and testis. Orthologous to human VSIG1 (V-set and immunoglobulin domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in stomach adult (RPKM 25.5), testis adult (RPKM 16.6) and 1 other tissue See more
    Orthologs
    NEW
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    Genomic context

    See Vsig1 in Genome Data Viewer
    Location:
    X F1; X 61.62 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (139808357..139840221)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (140907608..140939472)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene testis expressed 13B Neighboring gene ribosomal protein S7 pseudogene Neighboring gene STARR-seq mESC enhancer starr_48010 Neighboring gene STARR-positive B cell enhancer ABC_E3263 Neighboring gene STARR-seq mESC enhancer starr_48011 Neighboring gene proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 Neighboring gene autophagy related 4A, cysteine peptidase Neighboring gene STARR-positive B cell enhancer mm9_chrX:137591358-137591658 Neighboring gene collagen, type IV, alpha 6 Neighboring gene predicted gene, 39539

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (1)  1 citation

    General protein information

    Preferred Names
    V-set and immunoglobulin domain-containing protein 1
    Names
    cell surface A33 antigen
    glycoprotein A34

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359143.1NP_001346072.1  V-set and immunoglobulin domain-containing protein 1 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AK132956, BC145050
      UniProtKB/Swiss-Prot
      Q9D2J4, Q9D9J0, Q9DA22
      UniProtKB/TrEMBL
      B7ZN70
      Conserved Domains (2) summary
      pfam13927
      Location:180253
      Ig_3; Immunoglobulin domain
      cl11960
      Location:24165
      Ig; Immunoglobulin domain
    2. NM_026103.1NP_080379.1  V-set and immunoglobulin domain-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_080379.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains a different segment for its 5' UTR and lacks part of the 5' coding region with the use of a downstream start codon, compared to variant 1. The resulting protein (isoform 2) has a shorter N-terminus when it is compared to isoform 1.
      Source sequence(s)
      AK006862, AK132956
      UniProtKB/Swiss-Prot
      Q9D2J4
      Conserved Domains (3) summary
      smart00409
      Location:47122
      IG; Immunoglobulin
      cl11960
      Location:122
      Ig; Immunoglobulin domain
      cl29137
      Location:207252
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
    3. NM_030181.3NP_084457.2  V-set and immunoglobulin domain-containing protein 1 isoform 1 precursor

      See identical proteins and their annotated locations for NP_084457.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. It encodes the longer protein (isoform 1).
      Source sequence(s)
      AK132956
      Consensus CDS
      CCDS30443.1
      UniProtKB/Swiss-Prot
      Q9D2J4, Q9D9J0, Q9DA22
      UniProtKB/TrEMBL
      A0A0B4J1E9
      Related
      ENSMUSP00000033806.5, ENSMUST00000033806.5
      Conserved Domains (3) summary
      cd00096
      Location:159226
      Ig; Immunoglobulin domain
      smart00410
      Location:154229
      IG_like; Immunoglobulin like
      cl11960
      Location:25129
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      139808357..139840221
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006528631.5XP_006528694.1  V-set and immunoglobulin domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006528694.1

      Related
      ENSMUST00000127629.2
      Conserved Domains (3) summary
      smart00409
      Location:47122
      IG; Immunoglobulin
      cl11960
      Location:122
      Ig; Immunoglobulin domain
      cl29137
      Location:207252
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)