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    tspan7.L tetraspanin 7 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 379984, updated on 4-Nov-2024

    Summary

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    Official Symbol
    tspan7.L
    Official Full Name
    tetraspanin 7 L homeolog
    Primary source
    Xenbase:XB-GENE-941780
    Locus tag
    XELAEV_18012381mg
    See related
    EnsemblRapid:ENSXLAG00005024073 AllianceGenome:Xenbase:XB-GENE-941780
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    a15; mxs1; cd231; mrx58; ccg-b7; tm4sf2; tspan7; talla-1
    Summary
    Predicted to be located in membrane. Is expressed in ectoderm; mesoderm; vestibuloauditory system; and visual system. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 58. Orthologous to human TSPAN7 (tetraspanin 7). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See tspan7.L in Genome Data Viewer
    Location:
    chromosome: 2L
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (80729445..80798350)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (75317805..75387079)

    Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene synaptotagmin like 5 L homeolog Neighboring gene sushi repeat containing protein X-linked L homeolog Neighboring gene MID1 interacting protein 1 L homeolog Neighboring gene BCL6 corepressor L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of the tetraspanin family members Tspan3, Tspan4, Tspan5 and Tspan7 during Xenopus laevis embryonic development. Kashef J, et al. Gene Expr Patterns, 2013 Jan-Feb. PMID 22940433
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC54027

    Gene Ontology Provided by Xenbase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tetraspanin 7 L homeolog
    Names
    transmembrane 4 superfamily member 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001086823.1 → NP_001080292.1  tetraspanin 7 L homeolog

      See identical proteins and their annotated locations for NP_001080292.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044697
      UniProtKB/TrEMBL
      A0A974DMF0, Q7ZXL9
      Related
      ENSXLAP00005071431.1, ENSXLAT00005072968.1
      Conserved Domains (2) summary
      cd03161
      Location:110 → 213
      TM4SF2_6_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF2_6_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
      pfam00335
      Location:14 → 239
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      80729445..80798350
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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