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    plekha5 pleckstrin homology domain containing, family A member 5 [ Danio rerio (zebrafish) ]

    Gene ID: 567300, updated on 9-Dec-2024

    Summary

    Official Symbol
    plekha5provided by ZNC
    Official Full Name
    pleckstrin homology domain containing, family A member 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041210-25
    See related
    Ensembl:ENSDARG00000045870 AllianceGenome:ZFIN:ZDB-GENE-041210-25
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb16e08; si:ch211-239h19.1
    Summary
    Predicted to enable phosphatidylinositol phosphate binding activity. Predicted to be active in cytosol. Orthologous to human PLEKHA5 (pleckstrin homology domain containing A5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See plekha5 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (2948063..3145359, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (3017952..3215271, complement)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 3A, cGMP-inhibited Neighboring gene AE binding protein 2 Neighboring gene uncharacterized LOC137491498 Neighboring gene intestine-specific homeobox Neighboring gene protein bicaudal D homolog 1-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General protein information

    Preferred Names
    pleckstrin homology domain-containing family A member 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001327786.1 → NP_001314715.1  pleckstrin homology domain-containing family A member 5

      Status: VALIDATED

      Source sequence(s)
      BX088564, BX914207, LO018342
      UniProtKB/TrEMBL
      A0A8M1P9B3, A0A8M3AR53, F1R8A2
      Related
      ENSDARP00000099969.4, ENSDART00000112210.4
      Conserved Domains (3) summary
      cd13248
      Location:164 → 267
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:170 → 266
      PH; PH domain
      pfam00397
      Location:13 → 42
      WW; WW domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      2948063..3145359 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009300011.4 → XP_009298286.1  pleckstrin homology domain-containing family A member 5 isoform X26

      UniProtKB/TrEMBL
      A0A8M3AR53, A0A8M3B1H1
      Related
      ENSDARP00000105373.2, ENSDART00000127894.4
      Conserved Domains (3) summary
      cd13248
      Location:164 → 267
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:170 → 266
      PH; PH domain
      pfam00397
      Location:13 → 42
      WW; WW domain
    2. XM_068219714.1 → XP_068075815.1  pleckstrin homology domain-containing family A member 5 isoform X27

      UniProtKB/TrEMBL
      A0A8M3AR53
    3. XM_009300010.4 → XP_009298285.1  pleckstrin homology domain-containing family A member 5 isoform X25

      UniProtKB/TrEMBL
      A0A8M3AR53, A0A8M3ARD7
      Conserved Domains (3) summary
      cd13248
      Location:164 → 267
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:170 → 266
      PH; PH domain
      pfam00397
      Location:13 → 42
      WW; WW domain
    4. XM_068219713.1 → XP_068075814.1  pleckstrin homology domain-containing family A member 5 isoform X24

      UniProtKB/TrEMBL
      A0A8M3AR53
    5. XM_068219712.1 → XP_068075813.1  pleckstrin homology domain-containing family A member 5 isoform X23

      UniProtKB/TrEMBL
      A0A8M3AR53
    6. XM_005164474.5 → XP_005164531.1  pleckstrin homology domain-containing family A member 5 isoform X4

      UniProtKB/TrEMBL
      A0A8M2BBV2, A0A8M3AR53
      Conserved Domains (3) summary
      cd13248
      Location:164 → 267
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:170 → 266
      PH; PH domain
      pfam00397
      Location:13 → 42
      WW; WW domain
    7. XM_021475091.2 → XP_021330766.1  pleckstrin homology domain-containing family A member 5 isoform X20

      UniProtKB/TrEMBL
      A0A8M9PUM6, A0A8M9Q602
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl26472
      Location:720 → 911
      DUF3084; Protein of unknown function (DUF3084)
    8. XM_068219711.1 → XP_068075812.1  pleckstrin homology domain-containing family A member 5 isoform X22

      UniProtKB/TrEMBL
      A0A8M9PUM6
    9. XM_021475090.2 → XP_021330765.1  pleckstrin homology domain-containing family A member 5 isoform X18

      UniProtKB/TrEMBL
      A0A8M9PUM6, A0A8M9QBD7
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl26472
      Location:720 → 911
      DUF3084; Protein of unknown function (DUF3084)
    10. XM_068219710.1 → XP_068075811.1  pleckstrin homology domain-containing family A member 5 isoform X21

      UniProtKB/TrEMBL
      A0A8M9PUM6
    11. XM_021475089.2 → XP_021330764.1  pleckstrin homology domain-containing family A member 5 isoform X17

      UniProtKB/TrEMBL
      A0A8M9PUM6, A0A8M9Q0N0
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl26472
      Location:720 → 912
      DUF3084; Protein of unknown function (DUF3084)
    12. XM_068219715.1 → XP_068075816.1  pleckstrin homology domain-containing family A member 5 isoform X28

      UniProtKB/TrEMBL
      A0A8M9PUM6
    13. XM_021475086.2 → XP_021330761.1  pleckstrin homology domain-containing family A member 5 isoform X13

      UniProtKB/TrEMBL
      A0A8M9PUM6, A0A8M9Q5Z9
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl26472
      Location:721 → 929
      DUF3084; Protein of unknown function (DUF3084)
    14. XM_068219716.1 → XP_068075817.1  pleckstrin homology domain-containing family A member 5 isoform X29

      UniProtKB/TrEMBL
      A0A8M9PUM6
    15. XM_021475085.2 → XP_021330760.1  pleckstrin homology domain-containing family A member 5 isoform X12

      UniProtKB/TrEMBL
      A0A8M9PUM6, A0A8M9QBD3
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl26472
      Location:721 → 930
      DUF3084; Protein of unknown function (DUF3084)
    16. XM_021475082.2 → XP_021330757.1  pleckstrin homology domain-containing family A member 5 isoform X7

      UniProtKB/TrEMBL
      A0A8M9PHE0, A0A8M9PUM6
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl26472
      Location:721 → 957
      DUF3084; Protein of unknown function (DUF3084)
    17. XM_021475088.2 → XP_021330763.1  pleckstrin homology domain-containing family A member 5 isoform X16

      UniProtKB/TrEMBL
      A0A8M9PUM1, A0A8M9PUM6
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl25732
      Location:731 → 955
      SMC_N; RecF/RecN/SMC N terminal domain
    18. XM_021475081.2 → XP_021330756.1  pleckstrin homology domain-containing family A member 5 isoform X6

      UniProtKB/TrEMBL
      A0A8M9PUM6, A0A8M9Q5Z6
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl25732
      Location:731 → 955
      SMC_N; RecF/RecN/SMC N terminal domain
    19. XM_021475080.2 → XP_021330755.1  pleckstrin homology domain-containing family A member 5 isoform X5

      UniProtKB/TrEMBL
      A0A8M9PUM6, A0A8M9QBC6
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl26472
      Location:721 → 970
      DUF3084; Protein of unknown function (DUF3084)
    20. XM_068219708.1 → XP_068075809.1  pleckstrin homology domain-containing family A member 5 isoform X9

      UniProtKB/TrEMBL
      A0A8M9PUM6
    21. XM_021475078.2 → XP_021330753.1  pleckstrin homology domain-containing family A member 5 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PUL1, A0A8M9PUM6
      Conserved Domains (2) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
    22. XM_021475083.2 → XP_021330758.1  pleckstrin homology domain-containing family A member 5 isoform X8

      UniProtKB/TrEMBL
      A0A8M9PUL6, A0A8M9PUM6
      Conserved Domains (2) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
    23. XM_068219709.1 → XP_068075810.1  pleckstrin homology domain-containing family A member 5 isoform X10

      UniProtKB/TrEMBL
      A0A8M9PUM6
    24. XM_021475077.2 → XP_021330752.1  pleckstrin homology domain-containing family A member 5 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PHD6, A0A8M9PUM6
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl25732
      Location:822 → 983
      SMC_N; RecF/RecN/SMC N terminal domain
    25. XM_021475079.2 → XP_021330754.1  pleckstrin homology domain-containing family A member 5 isoform X3

      UniProtKB/TrEMBL
      A0A8M9PUM6, A0A8M9Q0M2
      Conserved Domains (3) summary
      cd13248
      Location:177 → 280
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00397
      Location:13 → 42
      WW; WW domain
      cl25732
      Location:822 → 983
      SMC_N; RecF/RecN/SMC N terminal domain
    26. XM_021475087.2 → XP_021330762.1  pleckstrin homology domain-containing family A member 5 isoform X14

      UniProtKB/TrEMBL
      A0A8M9PHE4, A0A8M9PUM6
      Conserved Domains (1) summary
      cd13248
      Location:107 → 210
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
    27. XM_005164479.5 → XP_005164536.1  pleckstrin homology domain-containing family A member 5 isoform X19

      UniProtKB/TrEMBL
      A0A8M2BBQ9, A0A8M3AR53
      Conserved Domains (2) summary
      cd13248
      Location:43 → 146
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:49 → 145
      PH; PH domain
    28. XM_009300003.3 → XP_009298278.1  pleckstrin homology domain-containing family A member 5 isoform X15

      UniProtKB/TrEMBL
      A0A8M3AR53, A0A8M3B8Q5
      Conserved Domains (2) summary
      cd13248
      Location:99 → 202
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:105 → 201
      PH; PH domain
    29. XM_021475084.2 → XP_021330759.1  pleckstrin homology domain-containing family A member 5 isoform X11

      UniProtKB/TrEMBL
      A0A8M9PUM6, A0A8M9Q0M6
      Conserved Domains (1) summary
      cd13248
      Location:112 → 215
      PH_PEPP1_2_3; Phosphoinositol 3-phosphate binding proteins 1, 2, and 3 pleckstrin homology (PH) domain

    RNA

    1. XR_002458106.2 RNA Sequence

    2. XR_002458107.2 RNA Sequence