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    dnai1.1 dynein, axonemal, intermediate chain 1, paralog 1 [ Danio rerio (zebrafish) ]

    Gene ID: 570363, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dnai1.1provided by ZNC
    Official Full Name
    dynein, axonemal, intermediate chain 1, paralog 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040910-7
    See related
    Ensembl:ENSDARG00000100081 AllianceGenome:ZFIN:ZDB-GENE-040910-7
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    dnai1; si:ch73-182i17.2
    Summary
    Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Acts upstream of or within determination of heart left/right asymmetry. Predicted to be part of outer dynein arm. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 1. Orthologous to human DNAI1 (dynein axonemal intermediate chain 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dnai1.1 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (18292535..18304018)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (18259177..18267366)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene bromodomain containing 3a Neighboring gene WD repeat domain 5 Neighboring gene uncharacterized LOC137488864 Neighboring gene RIMS binding protein 2a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia. Li Y, et al. PLoS Genet, 2016 Feb. PMID 26918822, Free PMC Article
    2. Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility. Zhao L, et al. Proc Natl Acad Sci U S A, 2013 Jul 30. PMID 23858445, Free PMC Article
    3. Comparative analysis of the testis and ovary transcriptomes in zebrafish by combining experimental and computational tools. Li Y, et al. Comp Funct Genomics, 2004. PMID 18629171, Free PMC Article
    4. Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing. Tang Q, et al. J Exp Med, 2017 Oct 2. PMID 28878000, Free PMC Article
    5. Systematic discovery of novel ciliary genes through functional genomics in the zebrafish. Choksi SP, et al. Development, 2014 Sep. PMID 25139857, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within determination of heart left/right asymmetry IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dynein axonemal intermediate chain 1
    Names
    dynein, axonemal, intermediate polypeptide 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      18292535..18304018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021469050.2 → XP_021324725.2  dynein axonemal intermediate chain 1

      Related
      ENSDARP00000134180.1, ENSDART00000170205.2
    Nucleotide Protein Strain
    Heading Accession and Version

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