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    eef1g eukaryotic translation elongation factor 1 gamma [ Danio rerio (zebrafish) ]

    Gene ID: 195822, updated on 9-Dec-2024

    Summary

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    Official Symbol
    eef1gprovided by ZNC
    Official Full Name
    eukaryotic translation elongation factor 1 gammaprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-020423-3
    See related
    Ensembl:ENSDARG00000056119 AllianceGenome:ZFIN:ZDB-GENE-020423-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    db03h10; fk76a09; mg:db03h10; wu:fk76a09
    Summary
    Predicted to enable translation elongation factor activity. Predicted to be involved in translational elongation. Predicted to act upstream of or within translation. Predicted to be active in cytoplasm and nucleus. Orthologous to human EEF1G (eukaryotic translation elongation factor 1 gamma). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See eef1g in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (26719740..26729289)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (26421635..26431184)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene neurogenin 1 Neighboring gene RNA polymerase II subunit G Neighboring gene AHNAK nucleoprotein Neighboring gene kelch-like family member 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Burket CT, et al. Transgenic Res, 2008 Apr. PMID 17968670, Free PMC Article
    2. Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing. Nepal C, et al. Nat Commun, 2020 Jan 10. PMID 31924754, Free PMC Article
    3. Generation of Cas9 transgenic zebrafish and their application in establishing an ERV-deficient animal model. Yang Z, et al. Biotechnol Lett, 2018 Dec. PMID 30244429, Free PMC Article
    4. Control of cranial ectomesenchyme fate by Nr2f nuclear receptors. Okeke C, et al. Development, 2022 Dec 1. PMID 36367707, Free PMC Article
    5. Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene-expressing transgenic zebrafish model. Li Y, et al. Dis Model Mech, 2019 Oct 17. PMID 31515263, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translational elongation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within translational elongation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    elongation factor 1-gamma
    Names
    EF-1-gamma
    eEF-1B gamma
    nan
    nearly normal

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173263.1 → NP_775370.1  elongation factor 1-gamma

      See identical proteins and their annotated locations for NP_775370.1

      Status: PROVISIONAL

      Source sequence(s)
      AY099512
      UniProtKB/Swiss-Prot
      Q6PE25
      UniProtKB/TrEMBL
      Q8JIU6
      Related
      ENSDARP00000072983.4, ENSDART00000078522.6
      Conserved Domains (4) summary
      cd03181
      Location:91 → 213
      GST_C_EF1Bgamma_like; Glutathione S-transferase C-terminal-like, alpha helical domain of the Gamma subunit of Elongation Factor 1B and similar proteins
      cd03044
      Location:4 → 82
      GST_N_EF1Bgamma; GST_N family, Gamma subunit of Elongation Factor 1B (EFB1gamma) subfamily; EF1Bgamma is part of the eukaryotic translation elongation factor-1 (EF1) complex which plays a central role in the elongation cycle during protein biosynthesis. EF1 consists of ...
      TIGR01262
      Location:5 → 201
      maiA; maleylacetoacetate isomerase
      pfam00647
      Location:280 → 386
      EF1G; Elongation factor 1 gamma, conserved domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      26719740..26729289
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6PE25.1 GenPept UniProtKB/Swiss-Prot:Q6PE25

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