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    KLF4 KLF transcription factor 4 [ Macaca fascicularis (crab-eating macaque) ]

    Gene ID: 101926136, updated on 3-Dec-2024

    Summary

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    Gene symbol
    KLF4
    Gene description
    KLF transcription factor 4
    See related
    Ensembl:ENSMFAG00000035870
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca fascicularis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See KLF4 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_05 current T2T-MFA8v1.0 (GCF_037993035.1) 15 NC_088389.1 (50626685..50631544)
    102 previous assembly MFA1912RKSv2 (GCF_012559485.2) 15 NC_052269.1 (77971028..77975884, complement)

    Chromosome 15 - NC_088389.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC107127615 Neighboring gene uncharacterized LOC123569168 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC135967575 Neighboring gene RAD23 homolog B, nucleotide excision repair protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Substitution rate and structural divergence of 5'UTR evolution: comparative analysis between human and cynomolgus monkey cDNAs. Osada N, et al. Mol Biol Evol, 2005 Oct. PMID 15944441
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Krueppel-like factor 4
    Names
    Kruppel like factor 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_037993035.1-RS_2024_05

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference T2T-MFA8v1.0

    Genomic

    1. NC_088389.1 Reference T2T-MFA8v1.0

      Range
      50626685..50631544
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005581122.4 → XP_005581179.2  Krueppel-like factor 4 isoform X1

      UniProtKB/TrEMBL
      A0A2K5VB57

    2. XM_045373588.2 → XP_045229523.1  Krueppel-like factor 4 isoform X2

      UniProtKB/TrEMBL
      A0A2K5VB57, Q4R355
      Conserved Domains (4) summary
      COG5048
      Location:391 → 474
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:398 → 420
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:442 → 467
      zf-H2C2_2; Zinc-finger double domain
      cd21582
      Location:7 → 396
      KLF4_N; N-terminal domain of Kruppel-like factor 4

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001285338.1: Suppressed sequence

      Description
      NM_001285338.1: This RefSeq record was removed as a result of standard genome annotation processing. Contact [email protected] for further information.
    Nucleotide Protein
    Heading Accession and Version

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