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    Eva1c eva-1 homolog C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360695, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Eva1cprovided by RGD
    Official Full Name
    eva-1 homolog Cprovided by RGD
    Primary source
    RGD:1307569
    See related
    EnsemblRapid:ENSRNOG00000002072 AllianceGenome:RGD:1307569
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam176c; RGD1307569
    Summary
    Predicted to enable heparin binding activity. Predicted to be located in membrane. Predicted to colocalize with extracellular region. Orthologous to human EVA1C (eva-1 homolog C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 22.7), Lung (RPKM 15.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Eva1c in Genome Data Viewer
    Location:
    11q11
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (43575613..43649677)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (30089510..30163596)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (31001697..31075784)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene melanocortin 2 receptor accessory protein Neighboring gene URB1 ribosome biogenesis homolog Neighboring gene uncharacterized LOC134481053 Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene cilia and flagella associated protein 298

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Human C21orf63 is a heparin-binding protein. Mitsunaga K, et al. J Biochem, 2009 Sep. PMID 19470522
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heparin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables heparin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    eva-1 homolog C; protein eva-1 homolog C
    Names
    family with sequence similarity 176, member C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001430789.1 → NP_001417718.1  eva-1 homolog C isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6JLD1, D4A895

    2. NM_001430790.1 → NP_001417719.1  eva-1 homolog C isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A0A8I5ZR28, A0A8I6AIF8

    RNA

    1. NR_190991.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011

    2. NR_190992.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      43575613..43649677
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039088774.2 → XP_038944702.1  protein eva-1 homolog C isoform X4

      Conserved Domains (2) summary
      pfam02140
      Location:75 → 158
      Gal_Lectin; Galactose binding lectin domain
      pfam14851
      Location:300 → 316
      FAM176; FAM176 family

    2. XM_017598089.3 → XP_017453578.1  protein eva-1 homolog C isoform X2

      UniProtKB/TrEMBL
      A6JLD1

    3. XM_340966.10 → XP_340967.4  protein eva-1 homolog C isoform X1

      Related
      ENSRNOP00000080620.2, ENSRNOT00000098199.2
      Conserved Domains (2) summary
      pfam02140
      Location:75 → 158
      Gal_Lectin; Galactose binding lectin domain
      pfam14851
      Location:300 → 440
      FAM176; FAM176 family

    4. XM_017598090.3 → XP_017453579.1  protein eva-1 homolog C isoform X3

      Related
      ENSRNOP00000088246.2, ENSRNOT00000113909.2

    RNA

    1. XR_010056249.1 RNA Sequence

      Related
      ENSRNOT00000002838.10
    Nucleotide Protein Strain
    Heading Accession and Version

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