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    EBF1 EBF transcription factor 1 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 462229, updated on 3-Dec-2024

    Summary

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    Official Symbol
    EBF1provided by VGNC
    Official Full Name
    EBF transcription factor 1provided by VGNC
    Primary source
    VGNC:VGNC:11935
    Locus tag
    CK820_G0010219
    See related
    Ensembl:ENSPTRG00000017477
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
    human mouse all
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    Genomic context

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    See EBF1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (156389397..156791612, complement)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (156410284..156812484, complement)

    Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene cell division cycle 37, HSP90 cochaperone Neighboring gene uracil-DNA glycosylase-like Neighboring gene uncharacterized LOC134810122 Neighboring gene uncharacterized LOC134810123 Neighboring gene ring finger protein 145

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor COE1
    Names
    early B cell factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      156389397..156791612 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063811625.1 → XP_063667695.1  transcription factor COE1 isoform X8

    2. XM_063811629.1 → XP_063667699.1  transcription factor COE1 isoform X12

    3. XM_063811624.1 → XP_063667694.1  transcription factor COE1 isoform X7

    4. XM_063811634.1 → XP_063667704.1  transcription factor COE1 isoform X19

      UniProtKB/TrEMBL
      A0A2I3SLB9

    5. XM_063811626.1 → XP_063667696.1  transcription factor COE1 isoform X10

    6. XM_063811642.1 → XP_063667712.1  transcription factor COE1 isoform X26

      UniProtKB/TrEMBL
      A0A2I3SLB9

    7. XM_063811633.1 → XP_063667703.1  transcription factor COE1 isoform X18

      UniProtKB/TrEMBL
      A0A2I3SLB9

    8. XM_063811632.1 → XP_063667702.1  transcription factor COE1 isoform X17

      UniProtKB/TrEMBL
      A0A2I3SLB9

    9. XM_009450060.5 → XP_009448335.1  transcription factor COE1 isoform X14

      See identical proteins and their annotated locations for XP_009448335.1

      Conserved Domains (3) summary
      cd01175
      Location:255 → 339
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21 → 247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:340 → 383
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain

    10. XM_063811645.1 → XP_063667715.1  transcription factor COE1 isoform X28

      UniProtKB/TrEMBL
      A0A2I3T6E5, A0A2J8NKC1, A0A6D2X4B3

    11. XM_063811643.1 → XP_063667713.1  transcription factor COE1 isoform X27

      UniProtKB/TrEMBL
      A0A2I3T6E5, A0A2J8NKC1, A0A6D2X4B3

    12. XM_063811640.1 → XP_063667710.1  transcription factor COE1 isoform X24

      UniProtKB/TrEMBL
      A0A2I3SLB9

    13. XM_063811647.1 → XP_063667717.1  transcription factor COE1 isoform X29

      UniProtKB/TrEMBL
      A0A2I3T6E5, A0A2J8NKC1, A0A6D2X4B3

    14. XM_063811646.1 → XP_063667716.1  transcription factor COE1 isoform X28

      UniProtKB/TrEMBL
      A0A2I3T6E5, A0A2J8NKC1, A0A6D2X4B3

    15. XM_063811644.1 → XP_063667714.1  transcription factor COE1 isoform X27

      UniProtKB/TrEMBL
      A0A2I3T6E5, A0A2J8NKC1, A0A6D2X4B3

    16. XM_063811641.1 → XP_063667711.1  transcription factor COE1 isoform X25

      UniProtKB/TrEMBL
      A0A2I3SLB9

    17. XM_063811639.1 → XP_063667709.1  transcription factor COE1 isoform X23

      UniProtKB/TrEMBL
      A0A2I3SLB9

    18. XM_063811623.1 → XP_063667693.1  transcription factor COE1 isoform X6

    19. XM_063811631.1 → XP_063667701.1  transcription factor COE1 isoform X16

      UniProtKB/TrEMBL
      A0A2I3SLB9

    20. XM_063811622.1 → XP_063667692.1  transcription factor COE1 isoform X5

    21. XM_063811621.1 → XP_063667691.1  transcription factor COE1 isoform X2

    22. XM_063811619.1 → XP_063667689.1  transcription factor COE1 isoform X1

    23. XM_016954132.3 → XP_016809621.1  transcription factor COE1 isoform X9

      UniProtKB/TrEMBL
      A0A2I3TI72
      Related
      ENSPTRP00000062030.1
      Conserved Domains (3) summary
      cd01175
      Location:254 → 338
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21 → 247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:339 → 382
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain

    24. XM_016954131.4 → XP_016809620.1  transcription factor COE1 isoform X15

      Conserved Domains (3) summary
      cd01175
      Location:255 → 339
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21 → 247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:340 → 383
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain

    25. XM_016954130.3 → XP_016809619.1  transcription factor COE1 isoform X4

      Conserved Domains (3) summary
      cd01175
      Location:262 → 346
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21 → 247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:347 → 390
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain

    26. XM_063811638.1 → XP_063667708.1  transcription factor COE1 isoform X22

      UniProtKB/TrEMBL
      A0A2I3SLB9

    27. XM_063811630.1 → XP_063667700.1  transcription factor COE1 isoform X13

      UniProtKB/TrEMBL
      A0A2I3SLB9

    28. XM_063811627.1 → XP_063667697.1  transcription factor COE1 isoform X11

      UniProtKB/TrEMBL
      A0A2I3SLB9

    29. XM_016954129.4 → XP_016809618.1  transcription factor COE1 isoform X3

      Conserved Domains (3) summary
      cd01175
      Location:263 → 347
      IPT_COE; IPT domain of the COE family (Col/Olf-1/EBF) of non-basic, helix-loop-helix (HLH)-containing transcription factors. COE family proteins are all transcription factors and play an important role in variety of developmental processes. Mouse EBF is involved ...
      pfam16422
      Location:21 → 247
      COE1_DBD; Transcription factor COE1 DNA-binding domain
      pfam16423
      Location:348 → 391
      COE1_HLH; Transcription factor COE1 helix-loop-helix domain

    30. XM_063811636.1 → XP_063667706.1  transcription factor COE1 isoform X21

      UniProtKB/TrEMBL
      A0A2I3SLB9

    31. XM_063811635.1 → XP_063667705.1  transcription factor COE1 isoform X20

      UniProtKB/TrEMBL
      A0A2I3SLB9
    Nucleotide Protein
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