uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: uqcrqprovided by ZNC
Official Full Name: ubiquinol-cytochrome c reductase, complex III subunit VIIprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-199
See related: Ensembl:ENSDARG00000029064 AllianceGenome:ZFIN:ZDB-GENE-040718-199
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:92848; mg:bb03b10
Summary: Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex III. Is expressed in central nervous system and cranial ganglion. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 4. Orthologous to human UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (38875078..38878455, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (38534764..38538141, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, ubiquinol to cytochrome c	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mitochondrial electron transport, ubiquinol to cytochrome c	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex III	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: cytochrome b-c1 complex subunit 8

NP_001002495.2

EC 7.1.1.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002495.3 → NP_001002495.2 cytochrome b-c1 complex subunit 8

Status: VALIDATED

Source sequence(s)

BX005218, EH545017

UniProtKB/TrEMBL

A0A8M1N0M1, F1QEJ5

Related

ENSDARP00000039787.5, ENSDART00000039788.6

Conserved Domains (1) summary

pfam02939
Location:4 → 79

UcrQ; UcrQ family