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    Paqr6 progestin and adipoQ receptor family member 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 681021, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Paqr6provided by RGD
    Official Full Name
    progestin and adipoQ receptor family member 6provided by RGD
    Primary source
    RGD:1584722
    See related
    EnsemblRapid:ENSRNOG00000026059 AllianceGenome:RGD:1584722
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable signaling receptor activity. Predicted to be located in membrane. Orthologous to human PAQR6 (progestin and adipoQ receptor family member 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 60.0), Brain (RPKM 29.6) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Paqr6 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176131345..176136266)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173832241..173838443)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187736774..187741696)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 79 Neighboring gene SMG5 nonsense mediated mRNA decay factor Neighboring gene bone gamma-carboxyglutamate protein Neighboring gene polyamine-modulated factor 1 Neighboring gene uncharacterized LOC134485637

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif. Tang YT, et al. J Mol Evol, 2005 Sep. PMID 16044242
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    membrane progestin receptor delta
    Names
    progestin and adipoQ receptor family member VI

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001191077.1 → NP_001178006.1  membrane progestin receptor delta

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      D4A4X5
      Related
      ENSRNOP00000075922.3, ENSRNOT00000092688.3
      Conserved Domains (1) summary
      pfam03006
      Location:43 → 271
      HlyIII; Haemolysin-III related

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      176131345..176136266
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063282525.1 → XP_063138595.1  membrane progestin receptor delta isoform X2

      UniProtKB/TrEMBL
      D4A4X5

    2. XM_017591101.3 → XP_017446590.2  membrane progestin receptor delta isoform X3

      UniProtKB/TrEMBL
      A0A0U1RS35, D4A4X5
      Related
      ENSRNOP00000075918.2, ENSRNOT00000092620.3
      Conserved Domains (1) summary
      pfam03006
      Location:58 → 286
      HlyIII; Haemolysin-III related

    3. XM_063282524.1 → XP_063138594.1  membrane progestin receptor delta isoform X1

      UniProtKB/TrEMBL
      D4A4X5

    4. XM_039103116.2 → XP_038959044.1  membrane progestin receptor delta isoform X4

      UniProtKB/TrEMBL
      D4A4X5
      Conserved Domains (1) summary
      cl03831
      Location:75 → 259
      HlyIII; Haemolysin-III related

    5. XM_008761213.4 → XP_008759435.1  membrane progestin receptor delta isoform X6

      UniProtKB/TrEMBL
      A0A0U1RS38
      Related
      ENSRNOP00000075881.3, ENSRNOT00000092653.3
      Conserved Domains (1) summary
      cl03831
      Location:103 → 193
      HlyIII; Haemolysin-III related

    6. XM_039103118.1 → XP_038959046.1  membrane progestin receptor delta isoform X5

      UniProtKB/TrEMBL
      D4A4X5
      Conserved Domains (1) summary
      pfam03006
      Location:19 → 247
      HlyIII; Haemolysin-III related

    7. XM_017591103.3 → XP_017446592.1  membrane progestin receptor delta isoform X5

      UniProtKB/TrEMBL
      D4A4X5
      Related
      ENSRNOP00000030755.6, ENSRNOT00000036143.9
      Conserved Domains (1) summary
      pfam03006
      Location:19 → 247
      HlyIII; Haemolysin-III related

    8. XM_063282527.1 → XP_063138597.1  membrane progestin receptor delta isoform X7

      UniProtKB/TrEMBL
      A0A0U1RS38

    9. XM_063282528.1 → XP_063138598.1  membrane progestin receptor delta isoform X8

    RNA

    1. XR_010063659.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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