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    Egfem1 EGF-like and EMI domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310269, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Egfem1provided by RGD
    Official Full Name
    EGF-like and EMI domain containing 1provided by RGD
    Primary source
    RGD:1307225
    See related
    EnsemblRapid:ENSRNOG00000023908 AllianceGenome:RGD:1307225
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307225
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jan 2025]
    Expression
    Biased expression in Brain (RPKM 31.9), Lung (RPKM 16.0) and 1 other tissue See more
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    Genomic context

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    See Egfem1 in Genome Data Viewer
    Location:
    2q24
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (115601768..116253029, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (113721236..114324547, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (116524965..117153933)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC134485612 Neighboring gene MDS1 and EVI1 complex locus Neighboring gene uncharacterized LOC134485895 Neighboring gene microRNA 551b Neighboring gene uncharacterized LOC134485730 Neighboring gene potassium calcium-activated channel subfamily M regulatory beta subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    EGF-like and EMI domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001415037.2 → NP_001401966.1  EGF-like and EMI domain-containing protein 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A8I5ZRX8
      Related
      ENSRNOP00000109213.1, ENSRNOT00000142244.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      115601768..116253029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281764.1 → XP_063137834.1  EGF-like and EMI domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I5Y2H5

    2. XM_063281767.1 → XP_063137837.1  EGF-like and EMI domain-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8I5ZRX8
      Related
      ENSRNOP00000034595.7, ENSRNOT00000039603.7

    3. XM_063281765.1 → XP_063137835.1  EGF-like and EMI domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I5Y2H5

    4. XM_017590848.3 → XP_017446337.3  EGF-like and EMI domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I5Y2H5
      Related
      ENSRNOP00000108504.1, ENSRNOT00000142746.1

    5. XM_063281768.1 → XP_063137838.1  EGF-like and EMI domain-containing protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A8I5ZRX8
      Related
      ENSRNOP00000110293.1, ENSRNOT00000132495.1

    6. XM_039102234.2 → XP_038958162.2  EGF-like and EMI domain-containing protein 1 isoform X4

      Related
      ENSRNOP00000111136.1, ENSRNOT00000160311.1

    7. XM_017590851.3 → XP_017446340.3  EGF-like and EMI domain-containing protein 1 isoform X7

      UniProtKB/TrEMBL
      A6IHM9, F1LWU8
      Related
      ENSRNOP00000081164.2, ENSRNOT00000097570.2

    RNA

    1. XR_010063603.1 RNA Sequence

    2. XR_005500283.2 RNA Sequence

    3. XR_010063604.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001107663.1: Suppressed sequence

      Description
      NM_001107663.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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