U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    COL1 CONSTANS-like 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831442, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    COL1
    Official Full Name
    CONSTANS-like 1
    Primary source
    TAIR:AT5G15850
    Locus tag
    AT5G15850
    See related
    Araport:AT5G15850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCOL1; B-box domain protein 2; BBX2; CONSTANS-like 1; F14F8.230; F14F8_230
    Summary
    Homologous to the flowering-time gene CONSTANS.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See COL1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (5176091..5177897, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene B-box type zinc finger protein with CCT domain-containing protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene prenylcysteine methylesterase Neighboring gene glycosyl hydrolase family 81 protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Specific missense alleles of the arabidopsis jasmonic acid co-receptor COI1 regulate innate immune receptor accumulation and function. He Y, et al. PLoS Genet, 2012. PMID 23093946, Free PMC Article
    2. Naturally occurring indel variation in the Brassica nigra COL1 gene is associated with variation in flowering time. Osterberg MK, et al. Genetics, 2002 May. PMID 12019243, Free PMC Article
    3. Mediator subunit MED25 links the jasmonate receptor to transcriptionally active chromatin. An C, et al. Proc Natl Acad Sci U S A, 2017 Oct 17. PMID 28973940, Free PMC Article
    4. Analysis of the function of two circadian-regulated CONSTANS-LIKE genes. Ledger S, et al. Plant J, 2001 Apr. PMID 11359606
    5. The sequence variation responsible for the functional difference between the CONSTANS protein, and the CONSTANS-like (COL) 1 and COL2 proteins, resides mostly in the region encoded by their first exons. Kim SK, et al. Plant Sci, 2013 Feb. PMID 23265320

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MED25 links COI1 with HAC1-dependent H3K9 acetylation to activate MYC2-regulated transcription of jasmonic acid-responsive genes.COI1 Is enriched on the promoters of JAZ8 and ERF1.
      Title: Mediator subunit MED25 links the jasmonate receptor to transcriptionally active chromatin.
    2. The lack of flowering promotion activity by COL1 and COL2 is mainly attributed to the differences between CO and the COL1 and COL2 proteins in the amino acid sequence encoded by their first exons.
      Title: The sequence variation responsible for the functional difference between the CONSTANS protein, and the CONSTANS-like (COL) 1 and COL2 proteins, resides mostly in the region encoded by their first exons.
    3. our data demonstrate a role for COI1 in disease resistance independent of Jasmonic Acid signaling and provide a molecular link between the JA and NB-LRR signaling pathways.
      Title: Specific missense alleles of the arabidopsis jasmonic acid co-receptor COI1 regulate innate immune receptor accumulation and function.
    4. Both COL1 and COR27 were found to be regulated by the circadian clock at warm growth temperatures.
      Title: A role for circadian evening elements in cold-regulated gene expression in Arabidopsis.
    5. The data demonstrate that ax6 enhances the effect of coi1 on JA responses, implying a genetic interaction between COI1 and AtCUL1 in JA signaling.
      Title: Point mutations in Arabidopsis Cullin1 reveal its essential role in jasmonate response.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_121590.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of flower development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    CONSTANS-like 1
    NP_197089.1
    • CONSTANS-like 1 (COL1); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity, zinc ion binding; INVOLVED IN: circadian rhythm, regulation of flower development; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: CCT domain (InterPro:IPR010402), Zinc finger, B-box (InterPro:IPR000315); BEST Arabidopsis thaliana protein match is: B-box type zinc finger protein with CCT domain (TAIR:AT5G15840.1); Has 3200 Blast hits to 2506 proteins in 141 species: Archae - 0; Bacteria - 0; Metazoa - 1; Fungi - 0; Plants - 3006; Viruses - 0; Other Eukaryotes - 193 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      5176091..5177897 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_121590.2 → NP_197089.1  CONSTANS-like 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197089.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O50055
      UniProtKB/TrEMBL
      A0A178U9N1, A0A5S9Y4H5, A0A654G1J6
      Conserved Domains (2) summary
      cd19821
      Location:11 → 54
      Bbox1_BBX-like; B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins
      pfam06203
      Location:286 → 329
      CCT; CCT motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O50055.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools