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    srrm4 serine/arginine repetitive matrix 4 [ Danio rerio (zebrafish) ]

    Gene ID: 796574, updated on 9-Dec-2024

    Summary

    Official Symbol
    srrm4provided by ZNC
    Official Full Name
    serine/arginine repetitive matrix 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050208-34
    See related
    Ensembl:ENSDARG00000086327 AllianceGenome:ZFIN:ZDB-GENE-050208-34
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    nSR100; ZnSR100; im:7136231; si:dkey-1k23.1
    Summary
    Predicted to enable mRNA binding activity. Involved in mRNA splicing, via spliceosome. Acts upstream of or within axonogenesis; facial nucleus development; and neuron maturation. Part of U2-type spliceosomal complex. Is expressed in head; nervous system; neural plate; and neural tube. Orthologous to human SRRM4 (serine/arginine repetitive matrix 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See srrm4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (15667866..15808369)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (15167564..15308139)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene TAO kinase 3a Neighboring gene SDS3 homolog, SIN3A corepressor complex component Neighboring gene uncharacterized LOC100151089 Neighboring gene uncharacterized LOC137490104 Neighboring gene si:dkey-1k23.3 Neighboring gene heat shock protein b8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within facial nucleus development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in mRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA splicing, via spliceosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in neuron maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within neuron maturation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of U2-type spliceosomal complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    serine/arginine repetitive matrix protein 4
    Names
    Neural-specific serine/arginine repetitive splicing factor of 100 kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001423807.1NP_001410736.1  serine/arginine repetitive matrix protein 4

      Status: VALIDATED

      Source sequence(s)
      BX649391, GFIL01039706
      UniProtKB/Swiss-Prot
      P0CB65
      UniProtKB/TrEMBL
      A0A0R4IL26, A0A8M9QEH5
      Related
      ENSDARP00000136286.1, ENSDART00000127015.3

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      15667866..15808369
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394571.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      178299..315781
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)