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    dnajc3b DnaJ (Hsp40) homolog, subfamily C, member 3b [ Danio rerio (zebrafish) ]

    Gene ID: 58154, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dnajc3bprovided by ZNC
    Official Full Name
    DnaJ (Hsp40) homolog, subfamily C, member 3bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000831-4
    See related
    Ensembl:ENSDARG00000017874 AllianceGenome:ZFIN:ZDB-GENE-000831-4
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    prkri; fc17a06; wu:fc17a06
    Summary
    Predicted to enable misfolded protein binding activity and protein-folding chaperone binding activity. Predicted to be involved in protein folding in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum. Orthologous to human DNAJC3 (DnaJ heat shock protein family (Hsp40) member C3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See dnajc3b in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (20780076..20797227, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (20539851..20556829, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene chromodomain helicase DNA binding protein 3 Neighboring gene cytochrome b5 domain containing 1 Neighboring gene uncharacterized LOC110439934 Neighboring gene claudin 15a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Induction of endoplasmic reticulum stress markers in an acromegaly model. Elbialy A, et al. J Cell Biochem, 2022 Sep. PMID 35734917
    2. Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis. Biswas G, et al. Mar Genomics, 2015 Aug. PMID 25792259
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables misfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein-folding chaperone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein folding in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    dnaJ homolog subfamily C member 3b
    Names
    protein-kinase, interferon-inducible double stranded RNA dependent inhibitor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131630.2 → NP_571705.2  dnaJ homolog subfamily C member 3b precursor

      Status: VALIDATED

      Source sequence(s)
      AL928637
      UniProtKB/TrEMBL
      Q9DDS8
      Related
      ENSDARP00000141699.2, ENSDART00000162357.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      20780076..20797227 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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