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    Fst Frost [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41169, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Fstprovided by FlyBase
    Official Full Name
    Frostprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037724
    Locus tag
    Dmel_CG9434
    See related
    AllianceGenome:FB:FBgn0037724
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9434; Dmel\CG9434; frost; fst
    Summary
    Involved in cold acclimation. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Fst in Genome Data Viewer
    Location:
    85E2-85E2; 3-49 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (9644978..9646154, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (5470700..5471876, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45053 Neighboring gene Spermidine Synthase Neighboring gene Sex comb on midleg Neighboring gene Diuretic hormone 44 Neighboring gene pseudo Neighboring gene Dynein heavy chain 1 Neighboring gene Neprilysin-like 12

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel gene that is up-regulated during recovery from cold shock in Drosophila melanogaster. Goto SG. Gene, 2001 May 30. PMID 11404024
    2. A proline repeat polymorphism of the Frost gene of Drosophila melanogaster showing clinal variation but not associated with cold resistance. Hoffmann AA, et al. Insect Mol Biol, 2012 Aug. PMID 22708613
    3. Increased abundance of frost mRNA during recovery from cold stress is not essential for cold tolerance in adult Drosophila melanogaster. Udaka H, et al. Insect Mol Biol, 2013 Oct. PMID 23901849
    4. Functional characterization of the Frost gene in Drosophila melanogaster: importance for recovery from chill coma. Colinet H, et al. PLoS One, 2010 Jun 2. PMID 20532197, Free PMC Article
    5. A comparison of Frost expression among species and life stages of Drosophila. Bing X, et al. Insect Mol Biol, 2012 Feb. PMID 21955087

    See all (70) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Fasting increases survival to cold in frost mutant Drosophila melanogaster.
      Title: Fasting increases survival to cold in FOXO, DIF, autophagy mutants and in other genotypes of Drosophila melanogaster.
    2. Cold-induced frost (Fst) accumulation is not essential for cold tolerance
      Title: Increased abundance of frost mRNA during recovery from cold stress is not essential for cold tolerance in adult Drosophila melanogaster.
    3. significantly upregulated in response to cold in eggs, third instar larvae, and 2- and 5-day-old male and female adults
      Title: A comparison of Frost expression among species and life stages of Drosophila.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cold acclimation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    frost
    Names
    CG9434-PA
    Fst-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      9644978..9646154 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_079570.4 → NP_524294.2  frost [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524294.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VH99
      Related
      FBpp0081579
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95RN4 Q95RN4
    Q9BH93 Q9BH93
    Q9VH99 Q9VH99

    Gene LinkOut

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