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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001318046.2 → NP_001304975.1 laminin subunit beta-4 isoform 1 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (1).
- Source sequence(s)
-
AC005048, AF028816, AK300385, BC144591
- Consensus CDS
-
CCDS34732.1
- UniProtKB/Swiss-Prot
- A4D0S4, A5PKU6, B2RTT3, B5MEB9, Q86TP7, Q86XN2, Q8NBX5
- UniProtKB/TrEMBL
-
B7ZMJ6
- Related
- ENSP00000205386.4, ENST00000205386.8
- Conserved Domains (5) summary
-
- cd00055
Location:454 → 503
- EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
- pfam00053
Location:1080 → 1128
- Laminin_EGF; Laminin EGF domain
- pfam00055
Location:38 → 263
- Laminin_N; Laminin N-terminal (Domain VI)
- pfam07926
Location:1609 → 1741
- TPR_MLP1_2; TPR/MLP1/MLP2-like protein
- cl21504
Location:938 → 967
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
-
NM_001318047.2 → NP_001304976.1 laminin subunit beta-4 isoform 2 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) lacks several exons, and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC005048, AF029325, AK300385, BC144591
- UniProtKB/TrEMBL
-
B4DTV7
- Related
-
ENST00000475469.1
- Conserved Domains (3) summary
-
- cd00055
Location:454 → 503
- EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
- pfam00053
Location:395 → 452
- Laminin_EGF; Laminin EGF domain
- pfam00055
Location:42 → 263
- Laminin_N; Laminin N-terminal (Domain VI)
-
NM_001318048.2 → NP_001304977.1 laminin subunit beta-4 isoform 3 precursor
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) lacks several exons, and uses an alternate 3'-terminal exon, compared to variant a. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3) has a shorter and distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC005048, AK300385, BC142619, BC144591
- Consensus CDS
-
CCDS83218.1
- UniProtKB/TrEMBL
- C9JM08, C9JMJ0, Q9UHI2
- Related
- ENSP00000402353.2, ENST00000418464.1
- Conserved Domains (4) summary
-
- cd00055
Location:454 → 503
- EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
- pfam00053
Location:395 → 452
- Laminin_EGF; Laminin EGF domain
- pfam00055
Location:42 → 263
- Laminin_N; Laminin N-terminal (Domain VI)
- pfam13900
Location:706 → 753
- GVQW; Putative domain of unknown function
-
NM_007356.3 → NP_031382.2 laminin subunit beta-4 isoform 1 precursor
See identical proteins and their annotated locations for NP_031382.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Both variants 1 and 2 encode the same isoform.
- Source sequence(s)
-
AC005048, AF028816, BC045172, DA859196
- Consensus CDS
-
CCDS34732.1
- UniProtKB/Swiss-Prot
- A4D0S4, A5PKU6, B2RTT3, B5MEB9, Q86TP7, Q86XN2, Q8NBX5
- UniProtKB/TrEMBL
-
B7ZMJ6
- Related
- ENSP00000373433.3, ENST00000388781.8
- Conserved Domains (5) summary
-
- cd00055
Location:454 → 503
- EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
- pfam00053
Location:1080 → 1128
- Laminin_EGF; Laminin EGF domain
- pfam00055
Location:38 → 263
- Laminin_N; Laminin N-terminal (Domain VI)
- pfam07926
Location:1609 → 1741
- TPR_MLP1_2; TPR/MLP1/MLP2-like protein
- cl21504
Location:938 → 967
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000007.14 Reference GRCh38.p14 Primary Assembly
- Range
-
108011662..108130361 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011515975.2 → XP_011514277.1 laminin subunit beta-4 isoform X1
- UniProtKB/TrEMBL
-
B7ZMJ6
- Conserved Domains (5) summary
-
- cd00055
Location:454 → 503
- EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
- TIGR04523
Location:1254 → 1714
- Mplasa_alph_rch; helix-rich Mycoplasma protein
- pfam00053
Location:1080 → 1128
- Laminin_EGF; Laminin EGF domain
- pfam00055
Location:38 → 263
- Laminin_N; Laminin N-terminal (Domain VI)
- cl21504
Location:938 → 967
- EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
-
XM_017011879.2 → XP_016867368.1 laminin subunit beta-4 isoform X2
- UniProtKB/TrEMBL
-
B7ZMJ6
-
XM_011515979.3 → XP_011514281.1 laminin subunit beta-4 isoform X4
- UniProtKB/TrEMBL
-
B7ZMJ6
- Conserved Domains (3) summary
-
- cd00055
Location:454 → 503
- EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
- pfam00053
Location:1080 → 1128
- Laminin_EGF; Laminin EGF domain
- pfam00055
Location:38 → 263
- Laminin_N; Laminin N-terminal (Domain VI)
-
XM_011515978.2 → XP_011514280.1 laminin subunit beta-4 isoform X3
- UniProtKB/TrEMBL
-
B7ZMJ6
- Conserved Domains (4) summary
-
- cd00055
Location:454 → 503
- EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
- TIGR04523
Location:1254 → 1714
- Mplasa_alph_rch; helix-rich Mycoplasma protein
- pfam00053
Location:1080 → 1128
- Laminin_EGF; Laminin EGF domain
- pfam00055
Location:38 → 263
- Laminin_N; Laminin N-terminal (Domain VI)
-
XM_011515980.3 → XP_011514282.1 laminin subunit beta-4 isoform X6
- UniProtKB/TrEMBL
-
B7ZMJ6
- Conserved Domains (3) summary
-
- cd00055
Location:454 → 503
- EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
- pfam00053
Location:1080 → 1128
- Laminin_EGF; Laminin EGF domain
- pfam00055
Location:38 → 263
- Laminin_N; Laminin N-terminal (Domain VI)
-
XM_017011880.2 → XP_016867369.1 laminin subunit beta-4 isoform X5
- UniProtKB/TrEMBL
-
B7ZMJ6
RNA
-
XR_927421.2 RNA Sequence
-
XR_927422.2 RNA Sequence
Alternate T2T-CHM13v2.0
Genomic
-
NC_060931.1 Alternate T2T-CHM13v2.0
- Range
-
109329907..109448507 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054357628.1 → XP_054213603.1 laminin subunit beta-4 isoform X1
- UniProtKB/TrEMBL
-
B7ZMJ6
-
XM_054357629.1 → XP_054213604.1 laminin subunit beta-4 isoform X2
- UniProtKB/TrEMBL
-
B7ZMJ6
-
XM_054357631.1 → XP_054213606.1 laminin subunit beta-4 isoform X4
- UniProtKB/TrEMBL
-
B7ZMJ6
-
XM_054357630.1 → XP_054213605.1 laminin subunit beta-4 isoform X3
- UniProtKB/TrEMBL
-
B7ZMJ6
-
XM_054357633.1 → XP_054213608.1 laminin subunit beta-4 isoform X6
- UniProtKB/TrEMBL
-
B7ZMJ6
-
XM_054357632.1 → XP_054213607.1 laminin subunit beta-4 isoform X5
- UniProtKB/TrEMBL
-
B7ZMJ6
RNA
-
XR_008487545.1 RNA Sequence
-
XR_008487546.1 RNA Sequence