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    GPRIN3 GPRIN family member 3 [ Homo sapiens (human) ]

    Gene ID: 285513, updated on 3-Dec-2024

    Summary

    Official Symbol
    GPRIN3provided by HGNC
    Official Full Name
    GPRIN family member 3provided by HGNC
    Primary source
    HGNC:HGNC:27733
    See related
    Ensembl:ENSG00000185477 MIM:611241; AllianceGenome:HGNC:27733
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GRIN3
    Summary
    Predicted to be involved in neuron projection development. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in appendix (RPKM 5.7), lymph node (RPKM 5.4) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See GPRIN3 in Genome Data Viewer
    Location:
    4q22.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (89236383..89307800, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (92567541..92638966, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (90157534..90228951, complement)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene RNA, U6 small nuclear 907, pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr4:90074054-90074582 Neighboring gene uncharacterized LOC124900834 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15568 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15569 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr4:90340115-90340640 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr4:90340641-90341165 Neighboring gene uncharacterized LOC105377328 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:90410728-90411320 Neighboring gene NANOG hESC enhancer GRCh37_chr4:90432809-90433310 Neighboring gene uncharacterized LOC124900855 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:90462817-90463325

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ42625

    Gene Ontology Provided by GOA

    Process Evidence Code Pubs
    involved_in neuron projection development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    G protein-regulated inducer of neurite outgrowth 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198281.3NP_938022.2  G protein-regulated inducer of neurite outgrowth 3

      See identical proteins and their annotated locations for NP_938022.2

      Status: VALIDATED

      Source sequence(s)
      AC093862, AC105388
      Consensus CDS
      CCDS34030.1
      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
      Related
      ENSP00000476603.1, ENST00000609438.2
      Conserved Domains (1) summary
      pfam15235
      Location:650771
      GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      89236383..89307800 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017008044.2XP_016863533.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
      Conserved Domains (1) summary
      pfam15235
      Location:650771
      GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
    2. XM_047450091.1XP_047306047.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
    3. XM_005262936.4XP_005262993.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      See identical proteins and their annotated locations for XP_005262993.1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
      Conserved Domains (1) summary
      pfam15235
      Location:650771
      GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
    4. XM_047450090.1XP_047306046.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
    5. XM_005262937.5XP_005262994.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      See identical proteins and their annotated locations for XP_005262994.1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
      Conserved Domains (1) summary
      pfam15235
      Location:650771
      GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
    6. XM_047450089.1XP_047306045.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
    7. XM_017008043.2XP_016863532.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
      Conserved Domains (1) summary
      pfam15235
      Location:650771
      GRIN_C; G protein-regulated inducer of neurite outgrowth C-terminus
    8. XM_047450093.1XP_047306049.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
    9. XM_047450092.1XP_047306048.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
      Related
      ENSP00000328672.3, ENST00000333209.4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      92567541..92638966 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054349731.1XP_054205706.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
    2. XM_054349730.1XP_054205705.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
    3. XM_054349729.1XP_054205704.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
    4. XM_054349726.1XP_054205701.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
    5. XM_054349728.1XP_054205703.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
    6. XM_054349727.1XP_054205702.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5
    7. XM_054349732.1XP_054205707.1  G protein-regulated inducer of neurite outgrowth 3 isoform X1

      UniProtKB/Swiss-Prot
      Q6ZVF9, Q8IVE4
      UniProtKB/TrEMBL
      A0AVI5

    RNA

    1. XR_007074276.1 RNA Sequence