Slc25a16 solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Slc25a16provided by MGI
Official Full Name: solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), member 16provided by MGI
Primary source: MGI:MGI:1920382
See related: Ensembl:ENSMUSG00000071253 AllianceGenome:MGI:1920382
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: GDA; GDC; ML7; HGT.1; 3110021G18Rik
Summary: Predicted to enable coenzyme A transmembrane transporter activity and secondary active transmembrane transporter activity. Predicted to be involved in coenzyme A biosynthetic process and mitochondrial coenzyme A transmembrane transport. Located in mitochondrion. Orthologous to human SLC25A16 (solute carrier family 25 member 16). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in kidney adult (RPKM 38.4), adrenal adult (RPKM 23.7) and 27 other tissues See more
Orthologs: human all
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Genomic context

Location:: 10 B4; 10 32.5 cM

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (62756454..62782278)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (62920632..62946494)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

Slc25a16 (e-PCR), detects polymorphism
- UniSTS:547038

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables coenzyme A transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables secondary active transmembrane transporter activity	ISO Inferred from Sequence Orthology more info	PubMed

Process	Evidence Code	Pubs
involved_in coenzyme A biosynthetic process	ISO Inferred from Sequence Orthology more info	PubMed
involved_in mitochondrial coenzyme A transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrial inner membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: solute carrier family 25 member 16

Names: graves disease carrier protein homolog; mitochondrial solute carrier protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001417857.1 → NP_001404786.1 solute carrier family 25 member 16 isoform 2

Status: VALIDATED

Source sequence(s)

AC153942
NM_175194.3 → NP_780403.1 solute carrier family 25 member 16 isoform 1

See identical proteins and their annotated locations for NP_780403.1

Status: VALIDATED

Source sequence(s)

AC153942

Consensus CDS

CCDS23893.1

UniProtKB/Swiss-Prot

B2RSS4, Q6P6K8, Q8C0K5

UniProtKB/TrEMBL

D3YVC9

Related

ENSMUSP00000043370.4, ENSMUST00000044977.10

Conserved Domains (2) summary

PTZ00169
Location:36 → 330

PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional

pfam00153
Location:33 → 125

Mito_carr; Mitochondrial carrier protein