mllt11 MLLT11 transcription factor 7 cofactor [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mllt11provided by ZNC
Official Full Name: MLLT11 transcription factor 7 cofactorprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-3007
See related: Ensembl:ENSDARG00000071026 AllianceGenome:ZFIN:ZDB-GENE-030131-3007
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc23g02; wu:fc23g02; si:ch211-210h11.4
Summary: Predicted to be involved in positive regulation of DNA-templated transcription; positive regulation of mitochondrial depolarization; and positive regulation of release of cytochrome c from mitochondria. Predicted to act upstream of or within apoptotic signaling pathway. Predicted to be located in centrosome; cytoplasm; and nucleus. Predicted to be active in cytosol and nucleoplasm. Is expressed in cranial ganglion; neurons; retina; retinal ganglion cell layer; and trigeminal placode. Orthologous to human MLLT11 (MLLT11 transcription factor 7 cofactor). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (7445644..7450792, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (7526719..7531867, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fj41c04.y1 (e-PCR)
- UniSTS:199306

fc23g02.x1 (e-PCR)
- UniSTS:187842

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within apoptotic signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of mitochondrial depolarization	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of release of cytochrome c from mitochondria	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein AF1q

Names: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

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These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.