U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    Nmd3 NMD3 ribosome export adaptor [ Mus musculus (house mouse) ]

    Gene ID: 97112, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Nmd3provided by MGI
    Official Full Name
    NMD3 ribosome export adaptorprovided by MGI
    Primary source
    MGI:MGI:2140103
    See related
    Ensembl:ENSMUSG00000027787 AllianceGenome:MGI:2140103
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable protein-macromolecule adaptor activity and ribosomal large subunit binding activity. Predicted to be involved in positive regulation of RNA biosynthetic process; positive regulation of protein localization to nucleolus; and ribosomal large subunit export from nucleus. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human NMD3 (NMD3 ribosome export adaptor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 13.4), CNS E11.5 (RPKM 10.0) and 28 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Nmd3 in Genome Data Viewer
    Location:
    3 E1- E2; 3 32.25 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (69629354..69656380)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (69722055..69749047)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 57714 Neighboring gene STARR-seq mESC enhancer starr_07930 Neighboring gene STARR-positive B cell enhancer ABC_E9552 Neighboring gene ribosomal protein L32, pseudogene Neighboring gene predicted gene, 52662 Neighboring gene STARR-seq mESC enhancer starr_07931 Neighboring gene ribosome production factor 2 homolog pseudogene Neighboring gene serine palmitoyltransferase, small subunit B Neighboring gene predicted gene, 52608

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each. Dogar AM, et al. PLoS One, 2018. PMID 30418981, Free PMC Article
    2. Identification of the ligands of protein interaction domains through a functional approach. Caratù G, et al. Mol Cell Proteomics, 2007 Feb. PMID 17124247
    3. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    4. ALS-linked loss of Cyclin-F function affects HSP90. Siebert A, et al. Life Sci Alliance, 2022 Sep 16. PMID 36114006, Free PMC Article
    5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-macromolecule adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ribosomal large subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ribosomal large subunit binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of RNA biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of RNA biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of protein localization to nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of protein localization to nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosomal large subunit export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within ribosomal large subunit export from nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in ribosomal large subunit export from nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    60S ribosomal export protein NMD3
    Names
    NMD3 homolog

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001411212.1 → NP_001398141.1  60S ribosomal export protein NMD3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    2. NM_001411213.1 → NP_001398142.1  60S ribosomal export protein NMD3 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    3. NM_001411214.1 → NP_001398143.1  60S ribosomal export protein NMD3 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    4. NM_001411215.1 → NP_001398144.1  60S ribosomal export protein NMD3 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    5. NM_001411216.1 → NP_001398145.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    6. NM_001411217.1 → NP_001398146.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    7. NM_001411218.1 → NP_001398147.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    8. NM_001411219.1 → NP_001398148.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    9. NM_001411220.1 → NP_001398149.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    10. NM_001411221.1 → NP_001398150.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    11. NM_001411222.1 → NP_001398151.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    12. NM_001411223.1 → NP_001398152.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    13. NM_001411224.1 → NP_001398153.1  60S ribosomal export protein NMD3 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    14. NM_001411225.1 → NP_001398154.1  60S ribosomal export protein NMD3 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790

    15. NM_133787.3 → NP_598548.1  60S ribosomal export protein NMD3 isoform 1

      See identical proteins and their annotated locations for NP_598548.1

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
      Consensus CDS
      CCDS17407.1
      UniProtKB/Swiss-Prot
      Q3UPR1, Q8BM61, Q99L48
      Related
      ENSMUSP00000029358.9, ENSMUST00000029358.15
      Conserved Domains (1) summary
      pfam04981
      Location:17 → 246
      NMD3; NMD3 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      69629354..69656380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99L48.1 GenPept UniProtKB/Swiss-Prot:Q99L48

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools