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    FYN FYN proto-oncogene, Src family tyrosine kinase [ Accipiter gentilis (Northern goshawk) ]

    Gene ID: 126046044, updated on 3-Aug-2024

    Summary

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    Gene symbol
    FYN
    Gene description
    FYN proto-oncogene, Src family tyrosine kinase
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Accipiter gentilis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Accipitrimorphae; Accipitriformes; Accipitridae; Accipitrinae; Accipiter
    Orthologs
    human mouse all
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    Genomic context

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    See FYN in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2023_02 current bAccGen1.1 (GCF_929443795.1) 15 NC_064894.1 (24775947..24916558)

    Chromosome 15 - NC_064894.1Genomic Context describing neighboring genes Neighboring gene laminin subunit alpha 4 Neighboring gene tubulin epsilon 1 Neighboring gene cellular communication network factor 6 Neighboring gene TRAF3 interacting protein 2 Neighboring gene REV3 like, DNA directed polymerase zeta catalytic subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_064894.1 Chromosome 15 Reference bAccGen1.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables non-membrane spanning protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in T cell receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extrinsic component of cytoplasmic side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    tyrosine-protein kinase Fyn

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_929443795.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bAccGen1.1

    Genomic

    1. NC_064894.1 Reference bAccGen1.1

      Range
      24775947..24916558
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_049817872.1 → XP_049673829.1  tyrosine-protein kinase Fyn isoform X1

      Conserved Domains (3) summary
      cd10418
      Location:145 → 245
      SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
      cd12006
      Location:85 → 140
      SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
      cd05070
      Location:261 → 534
      PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

    2. XM_049817877.1 → XP_049673834.1  tyrosine-protein kinase Fyn isoform X1

      Conserved Domains (3) summary
      cd10418
      Location:145 → 245
      SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
      cd12006
      Location:85 → 140
      SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
      cd05070
      Location:261 → 534
      PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

    3. XM_049817875.1 → XP_049673832.1  tyrosine-protein kinase Fyn isoform X1

      Conserved Domains (3) summary
      cd10418
      Location:145 → 245
      SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
      cd12006
      Location:85 → 140
      SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
      cd05070
      Location:261 → 534
      PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

    4. XM_049817876.1 → XP_049673833.1  tyrosine-protein kinase Fyn isoform X1

      Conserved Domains (3) summary
      cd10418
      Location:145 → 245
      SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
      cd12006
      Location:85 → 140
      SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
      cd05070
      Location:261 → 534
      PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

    5. XM_049817873.1 → XP_049673830.1  tyrosine-protein kinase Fyn isoform X1

      Conserved Domains (3) summary
      cd10418
      Location:145 → 245
      SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
      cd12006
      Location:85 → 140
      SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
      cd05070
      Location:261 → 534
      PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn

    6. XM_049817878.1 → XP_049673835.1  tyrosine-protein kinase Fyn isoform X2

    7. XM_049817874.1 → XP_049673831.1  tyrosine-protein kinase Fyn isoform X1

      Conserved Domains (3) summary
      cd10418
      Location:145 → 245
      SH2_Src_Fyn_isoform_a_like; Src homology 2 (SH2) domain found in Fyn isoform a like proteins
      cd12006
      Location:85 → 140
      SH3_Fyn_Yrk; Src homology 3 domain of Fyn and Yrk Protein Tyrosine Kinases
      cd05070
      Location:261 → 534
      PTKc_Fyn; Catalytic domain of the Protein Tyrosine Kinase, Fyn
    Nucleotide Protein
    Heading Accession and Version

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