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    ketose-bisphosphate aldolase class-II family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838407, updated on 18-Sep-2024

    Summary

    Official Full Name
    ketose-bisphosphate aldolase class-II family protein
    Primary source
    TAIR:AT1G18270
    Locus tag
    AT1G18270
    See related
    Araport:AT1G18270
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T10O22.24; T10O22_24
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    Genomic context

    Location:
    chromosome: 1
    Exon count:
    42
    Sequence:
    Chromosome: 1; NC_003070.9 (6283370..6293993, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene HCP-like superfamily protein Neighboring gene zein-binding protein (Protein of unknown function, DUF593) Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene DUF4228 domain protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001123831.1
    NM_001198099.1
    NM_001332339.1
    NM_101685.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables NADP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables aldehyde-lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    ketose-bisphosphate aldolase class-II family protein
    NP_001117303.1
    • ketose-bisphosphate aldolase class-II family protein; FUNCTIONS IN: in 8 functions; INVOLVED IN: oxidation reduction, pentose-phosphate shunt, valine metabolic process, glycolysis, metabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), Ketose-bisphosphate aldolase, class-II (InterPro:IPR000771), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), Protein of unknown function, DUF1537 (InterPro:IPR010737), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: 6-phosphogluconate dehydrogenase family protein (TAIR:AT4G20930.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001185028.1
    • ketose-bisphosphate aldolase class-II family protein; FUNCTIONS IN: in 8 functions; INVOLVED IN: oxidation reduction, pentose-phosphate shunt, valine metabolic process, glycolysis, metabolic process; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), Ketose-bisphosphate aldolase, class-II (InterPro:IPR000771), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), Protein of unknown function, DUF1537 (InterPro:IPR010737), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: 6-phosphogluconate dehydrogenase family protein (TAIR:AT4G20930.1).
    NP_173263.2
    • ketose-bisphosphate aldolase class-II family protein; FUNCTIONS IN: in 8 functions; INVOLVED IN: oxidation reduction, pentose-phosphate shunt, valine metabolic process, glycolysis, metabolic process; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), 6-phosphogluconate dehydrogenase, NAD-binding (InterPro:IPR006115), 6-phosphogluconate dehydrogenase, C-terminal-like (InterPro:IPR008927), Dehydrogenase, multihelical (InterPro:IPR013328), Ketose-bisphosphate aldolase, class-II (InterPro:IPR000771), 3-hydroxyacid dehydrogenase/reductase (InterPro:IPR015815), Protein of unknown function, DUF1537 (InterPro:IPR010737), NAD(P)-binding domain (InterPro:IPR016040), 3-hydroxyisobutyrate dehydrogenase-related, conserved site (InterPro:IPR002204); BEST Arabidopsis thaliana protein match is: 6-phosphogluconate dehydrogenase family protein (TAIR:AT4G20930.1); Has 34046 Blast hits to 22505 proteins in 2700 species: Archae - 264; Bacteria - 21742; Metazoa - 568; Fungi - 820; Plants - 423; Viruses - 1; Other Eukaryotes - 10228 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6283370..6293993 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101685.5NP_173263.2  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173263.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9UZZ2, A0A654ECE6, Q8VYC5
      Conserved Domains (1) summary
      PLN02858
      Location:11373
      PLN02858; fructose-bisphosphate aldolase
    2. NM_001332339.1NP_001322878.1  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AVD8, A0A5S9UZZ2
    3. NM_001123831.1NP_001117303.1  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117303.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9UZZ2, B3H739
      Conserved Domains (7) summary
      PLN02858
      Location:11374
      PLN02858; fructose-bisphosphate aldolase
      pfam01116
      Location:10981373
      F_bP_aldolase; Fructose-bisphosphate aldolase class-II
      pfam03446
      Location:324484
      NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase
      pfam07005
      Location:656894
      DUF1537; Putative sugar-binding N-terminal domain
      pfam14833
      Location:489609
      NAD_binding_11; NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
      pfam17042
      Location:9181084
      DUF1357_C; Putative nucleotide-binding of sugar-metabolizing enzyme
      cl21454
      Location:5158
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    4. NM_001198099.1NP_001185028.1  ketose-bisphosphate aldolase class-II family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185028.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9UZZ2, F4IAP5
      Conserved Domains (7) summary
      PLN02858
      Location:11393
      PLN02858; fructose-bisphosphate aldolase
      pfam01116
      Location:11171392
      F_bP_aldolase; Fructose-bisphosphate aldolase class-II
      pfam03446
      Location:323483
      NAD_binding_2; NAD binding domain of 6-phosphogluconate dehydrogenase
      pfam07005
      Location:655913
      DUF1537; Putative sugar-binding N-terminal domain
      pfam14833
      Location:488608
      NAD_binding_11; NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
      pfam17042
      Location:9371103
      DUF1357_C; Putative nucleotide-binding of sugar-metabolizing enzyme
      cl21454
      Location:5157
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins