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    CPZ Metallo-hydrolase/oxidoreductase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814995, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CPZ
    Official Full Name
    Metallo-hydrolase/oxidoreductase superfamily protein
    Primary source
    TAIR:AT2G04530
    Locus tag
    AT2G04530
    See related
    Araport:AT2G04530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T1O3.6; T1O3_6; TRNASE Z 2; TRZ2
    Summary
    Encodes a protein with RNAse Z activity suggesting a role in tRNA processing. Protein contains a signal sequence for import into the chloroplast.
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    Genomic context

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    See CPZ in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Sequence:
    Chromosome: 2; NC_003071.7 (1576694..1578962)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Nucleic acid-binding, OB-fold-like protein Neighboring gene Beta-ketoacyl synthase Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Assigning a function to a conserved group of proteins: the tRNA 3'-processing enzymes. Schiffer S, et al. EMBO J, 2002 Jun 3. PMID 12032089, Free PMC Article
    2. Arabidopsis encodes four tRNase Z enzymes. Canino G, et al. Plant Physiol, 2009 Jul. PMID 19411372, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_126484.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3'-tRNA processing endoribonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within tRNA 3'-end processing IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within tRNA processing TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Metallo-hydrolase/oxidoreductase superfamily protein
    NP_178532.2
    • CPZ; CONTAINS InterPro DOMAIN/s: Beta-lactamase-like (InterPro:IPR001279); BEST Arabidopsis thaliana protein match is: tRNAse Z1 (TAIR:AT1G74700.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      1576694..1578962
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126484.5 → NP_178532.2  Metallo-hydrolase/oxidoreductase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178532.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L633, Q8LGU8, Q9SJB8
      UniProtKB/TrEMBL
      A0A178VZE6, A0A5S9WX57, A0A654EWV5
      Conserved Domains (1) summary
      cd16272
      Location:89 → 278
      RNaseZ_MBL-fold; Ribonuclease Z; MBL-fold metallo-hydrolase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L633.1

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