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    EMC10 ER membrane protein complex subunit 10 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40396, updated on 9-Dec-2024

    Summary

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    Official Symbol
    EMC10provided by FlyBase
    Official Full Name
    ER membrane protein complex subunit 10provided by FlyBase
    Primary source
    FLYBASE:FBgn0052441
    Locus tag
    Dmel_CG32441
    See related
    AllianceGenome:FB:FBgn0052441
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32441; CG7783; Dmel\CG32441; emc10
    Summary
    Part of EMC complex. Is expressed in adult head. Orthologous to human EMC10 (ER membrane protein complex subunit 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See EMC10 in Genome Data Viewer
    Location:
    78D7-78D7; 3-47 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (21574131..21575874)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (21567231..21568974)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Structural maintenance of chromosomes 5 Neighboring gene long non-coding RNA:CR43939 Neighboring gene hairpin RNA:CR46340 Neighboring gene mir-193 stem loop Neighboring gene Transcription factor AP-2 Neighboring gene long non-coding RNA:CR43940

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. highroad Is a Carboxypetidase Induced by Retinoids to Clear Mutant Rhodopsin-1 in Drosophila Retinitis Pigmentosa Models. Huang HW, et al. Cell Rep, 2018 Feb 6. PMID 29425495, Free PMC Article
    2. ER complex proteins are required for rhodopsin biosynthesis and photoreceptor survival in Drosophila and mice. Xiong L, et al. Cell Death Differ, 2020 Feb. PMID 31263175, Free PMC Article
    3. Non-random genomic integration - an intrinsic property of retrogenes in Drosophila? Metta M, et al. BMC Evol Biol, 2010 Apr 28. PMID 20426838, Free PMC Article
    4. Stem Cell-Intrinsic, Seven-up-Triggered Temporal Factor Gradients Diversify Intermediate Neural Progenitors. Ren Q, et al. Curr Biol, 2017 May 8. PMID 28434858
    5. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    part_of EMC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of EMC complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ER membrane protein complex subunit 10
    Names
    CG32441-PC
    CG32441-PD
    EMC10-PC
    EMC10-PD
    endoplasmic reticulum membrane protein complex 10

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      21574131..21575874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168925.2 → NP_730661.2  ER membrane protein complex subunit 10, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730661.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8E6M8, Q8IPT1

    2. NM_168926.3 → NP_730662.2  ER membrane protein complex subunit 10, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730662.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6AWP4, Q8IPT0
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AWP4 Q6AWP4
    Q8IPT0 Q8IPT0
    Q8IPT1 Q8IPT1

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