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    STARD8 StAR related lipid transfer domain containing 8 [ Gallus gallus (chicken) ]

    Gene ID: 121113224, updated on 3-Dec-2024

    Summary

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    Symbol
    STARD8provided by CGNC
    Full Name
    StAR related lipid transfer domain containing 8provided by CGNC
    Primary source
    CGNC:3383
    See related
    Ensembl:ENSGALG00010015834
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See STARD8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (514573..556788)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (550789..593068)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene oligophrenin 1 Neighboring gene uncharacterized LOC121110541 Neighboring gene Yip1 domain family member 6 Neighboring gene microRNA 6594 Neighboring gene relaxin/insulin-like family peptide receptor 2 Neighboring gene uncharacterized LOC121110542 Neighboring gene uncharacterized LOC101748689

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    stAR-related lipid transfer protein 8
    Names
    START domain containing 8
    StAR-related lipid transfer (START) domain containing 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      514573..556788
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040699969.2 → XP_040555903.1  stAR-related lipid transfer protein 8 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z065, A0A8V0Z070
      Related
      ENSGALP00010022018.1, ENSGALT00010038151.1
      Conserved Domains (3) summary
      cd08907
      Location:869 → 1073
      START_STARD8-like; C-terminal lipid-binding START domain of mammalian STARD8 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
      cd09538
      Location:31 → 90
      SAM_DLC1,2-like; SAM domain of DLC1,2-like subfamily
      cd04375
      Location:628 → 844
      RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

    2. XM_046940744.1 → XP_046796700.1  stAR-related lipid transfer protein 8 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z065

    3. XM_040699968.2 → XP_040555902.1  stAR-related lipid transfer protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z065
      Conserved Domains (3) summary
      cd08907
      Location:878 → 1082
      START_STARD8-like; C-terminal lipid-binding START domain of mammalian STARD8 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
      cd09538
      Location:40 → 99
      SAM_DLC1,2-like; SAM domain of DLC1,2-like subfamily
      cd04375
      Location:637 → 853
      RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

    4. XM_040699973.2 → XP_040555907.1  stAR-related lipid transfer protein 8 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z065
      Conserved Domains (2) summary
      cd08907
      Location:789 → 993
      START_STARD8-like; C-terminal lipid-binding START domain of mammalian STARD8 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
      cd04375
      Location:548 → 764
      RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

    5. XM_046940743.1 → XP_046796699.1  stAR-related lipid transfer protein 8 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z065

    6. XM_040699970.2 → XP_040555904.1  stAR-related lipid transfer protein 8 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YTF1, A0A8V0Z065
      Related
      ENSGALP00010022008.1, ENSGALT00010038137.1
      Conserved Domains (3) summary
      cd08907
      Location:867 → 1071
      START_STARD8-like; C-terminal lipid-binding START domain of mammalian STARD8 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
      cd09538
      Location:29 → 88
      SAM_DLC1,2-like; SAM domain of DLC1,2-like subfamily
      cd04375
      Location:626 → 842
      RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

    7. XM_040699972.2 → XP_040555906.1  stAR-related lipid transfer protein 8 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YVA1, A0A8V0Z065
      Related
      ENSGALP00010022004.1, ENSGALT00010038133.1
      Conserved Domains (3) summary
      cd08907
      Location:855 → 1059
      START_STARD8-like; C-terminal lipid-binding START domain of mammalian STARD8 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
      cd09538
      Location:17 → 76
      SAM_DLC1,2-like; SAM domain of DLC1,2-like subfamily
      cd04375
      Location:614 → 830
      RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

    8. XM_046940742.1 → XP_046796698.1  stAR-related lipid transfer protein 8 isoform X5

      UniProtKB/TrEMBL
      A0A8V0YVA1, A0A8V0Z065

    9. XM_040699971.2 → XP_040555905.1  stAR-related lipid transfer protein 8 isoform X4

      UniProtKB/TrEMBL
      A0A8V0YM14, A0A8V0Z065
      Related
      ENSGALP00010022006.1, ENSGALT00010038135.1
      Conserved Domains (3) summary
      cd08907
      Location:858 → 1062
      START_STARD8-like; C-terminal lipid-binding START domain of mammalian STARD8 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
      cd09538
      Location:20 → 79
      SAM_DLC1,2-like; SAM domain of DLC1,2-like subfamily
      cd04375
      Location:617 → 833
      RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

    10. XM_046940745.1 → XP_046796701.1  stAR-related lipid transfer protein 8 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z065

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      550789..593068
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046916703.1 → XP_046772659.1  stAR-related lipid transfer protein 8 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Z065

    2. XM_046916710.1 → XP_046772666.1  stAR-related lipid transfer protein 8 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z065

    3. XM_046916702.1 → XP_046772658.1  stAR-related lipid transfer protein 8 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Z065

    4. XM_046916708.1 → XP_046772664.1  stAR-related lipid transfer protein 8 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z065

    5. XM_046916709.1 → XP_046772665.1  stAR-related lipid transfer protein 8 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z065

    6. XM_046916704.1 → XP_046772660.1  stAR-related lipid transfer protein 8 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Z065

    7. XM_046916706.1 → XP_046772662.1  stAR-related lipid transfer protein 8 isoform X5

      UniProtKB/TrEMBL
      A0A8V0Z065

    8. XM_046916707.1 → XP_046772663.1  stAR-related lipid transfer protein 8 isoform X5

      UniProtKB/TrEMBL
      A0A8V0Z065

    9. XM_046916705.1 → XP_046772661.1  stAR-related lipid transfer protein 8 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Z065

    10. XM_046916711.1 → XP_046772667.1  stAR-related lipid transfer protein 8 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Z065
    Nucleotide Protein
    Heading Accession and Version

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