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    AGO9 Argonaute family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832241, updated on 14-Nov-2024

    Summary

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    Official Symbol
    AGO9
    Official Full Name
    Argonaute family protein
    Primary source
    TAIR:AT5G21150
    Locus tag
    AT5G21150
    See related
    Araport:AT5G21150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARGONAUTE 9; T10F18.180; T10F18_180
    Summary
    AGO9-dependent sRNA silencing is crucial to specify cell fate in the Arabidopsis ovule. AGO9 is expressed in reproductive companion cells but not in the associated male or female gametes or their precursors. Therefore, AGO9 acts non-cell autonomously to silencing the activity of TEs activity in the female gametophyte.
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    Genomic context

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    See AGO9 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    23
    Sequence:
    Chromosome: 5; NC_003076.8 (7192239..7198381)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Neighboring gene embryo defective 1379 Neighboring gene LA RNA-binding protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The miRNA822 loaded by ARGONAUTE9 modulates the monosporic female gametogenesis in Arabidopsis thaliana. Tovar-Aguilar A, et al. Plant Reprod, 2024 Jun. PMID 38019279
    2. Natural variation in epigenetic pathways affects the specification of female gamete precursors in Arabidopsis. Rodríguez-Leal D, et al. Plant Cell, 2015 Apr. PMID 25829442, Free PMC Article
    3. Meiosis-specific gene discovery in plants: RNA-Seq applied to isolated Arabidopsis male meiocytes. Chen C, et al. BMC Plant Biol, 2010 Dec 17. PMID 21167045, Free PMC Article
    4. ARGONAUTE9-dependent silencing of transposable elements in pericentromeric regions of Arabidopsis. Durán-Figueroa N, et al. Plant Signal Behav, 2010 Nov. PMID 21057207, Free PMC Article
    5. Control of female gamete formation by a small RNA pathway in Arabidopsis. Olmedo-Monfil V, et al. Nature, 2010 Mar 25. PMID 20208518, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The miRNA822 loaded by ARGONAUTE9 modulates the monosporic female gametogenesis in Arabidopsis thaliana.
      Title: The miRNA822 loaded by ARGONAUTE9 modulates the monosporic female gametogenesis in Arabidopsis thaliana.
    2. AGO9 can bind to 24 retrotransposons and its predominant transposable element targets are in the pericentromeric regions of all 5 chromosomes.
      Title: ARGONAUTE9-dependent silencing of transposable elements in pericentromeric regions of Arabidopsis.
    3. Data show that AGO9 gene (At5G21150) was preferentially expressed in anthers versus meiocytes (M/A = 78.24/172.37), which is consistent with the discovery of a postmeiotic function.
      Title: Meiosis-specific gene discovery in plants: RNA-Seq applied to isolated Arabidopsis male meiocytes.
    4. Arabidopsis protein ARGONAUTE 9 (AGO9) controls female gamete formation by restricting the specification of gametophyte precursors in a dosage-dependent, non-cell-autonomous manner. [ARGONAUTE 9] [AGO9]
      Title: Control of female gamete formation by a small RNA pathway in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_122122.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables siRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to virus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within megasporocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within megasporogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within plant ovule development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within transposable element silencing IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Argonaute family protein
    NP_197613.2
    • ARGONAUTE 9 (AGO9); FUNCTIONS IN: siRNA binding; INVOLVED IN: ovule development, negative regulation of transposition; LOCATED IN: cytoplasm; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Domain of unknown function DUF1785 (InterPro:IPR014811), Stem cell self-renewal protein Piwi (InterPro:IPR003165), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), Argonaute/Dicer protein, PAZ (InterPro:IPR003100); BEST Arabidopsis thaliana protein match is: Argonaute family protein (TAIR:AT2G27040.2); Has 1875 Blast hits to 1834 proteins in 208 species: Archae - 0; Bacteria - 0; Metazoa - 980; Fungi - 283; Plants - 463; Viruses - 0; Other Eukaryotes - 149 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      7192239..7198381
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_122122.3 → NP_197613.2  Argonaute family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_197613.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56X15, Q84VQ0, Q84YI4
      UniProtKB/TrEMBL
      A0A5S9Y628, A0A654G2Z7
      Conserved Domains (1) summary
      PLN03202
      Location:17 → 896
      PLN03202; protein argonaute; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84VQ0.2

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