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    CG4022 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39082, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4022provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035986
    Locus tag
    Dmel_CG4022
    See related
    AllianceGenome:FB:FBgn0035986
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4022
    Summary
    Predicted to be active in cytoplasm. Is expressed in several structures, including central brain primordium; embryonic/larval midgut; embryonic/larval midgut primordium; ganglia; and larval nervous system. Orthologous to human PIH1D2 (PIH1 domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4022 in Genome Data Viewer
    Location:
    67B4-67B5; 3-29 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9406179..9410832, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9399279..9403932, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E1 Neighboring gene Cuticular protein 67B Neighboring gene Cleavage and polyadenylation specific factor 5 Neighboring gene alpha-tubulin acetylase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of JAK/STAT signalling components by genome-wide RNA interference. Müller P, et al. Nature, 2005 Aug 11. PMID 16094372
    2. The Drosophila retinoblastoma binding protein 6 family member has two isoforms and is potentially involved in embryonic patterning. Hull R, et al. Int J Mol Sci, 2015 May 6. PMID 25955646, Free PMC Article
    3. The soluble proteome of the Drosophila antenna. Anholt RR, et al. Chem Senses, 2010 Jan. PMID 19917591, Free PMC Article
    4. An RNAi-mediated screen identifies novel targets for next-generation antiepileptic drugs based on increased expression of the homeostatic regulator pumilio. Lin WH, et al. J Neurogenet, 2018 Mar-Jun. PMID 29718742, Free PMC Article
    5. Unraveling the Genetic Basis for the Rapid Diversification of Male Genitalia between Drosophila Species. Hagen JFD, et al. Mol Biol Evol, 2021 Jan 23. PMID 32931587, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4022-PA
    CG4022-PB
    CG4022-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9406179..9410832 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259768.2 → NP_001246697.1  uncharacterized protein Dmel_CG4022, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246697.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSY1
      Conserved Domains (1) summary
      cl00175
      Location:106 → 196
      alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.

    2. NM_001259767.2 → NP_001246696.1  uncharacterized protein Dmel_CG4022, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246696.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSY1
      Conserved Domains (1) summary
      cl00175
      Location:106 → 196
      alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.

    3. NM_140050.4 → NP_648307.1  uncharacterized protein Dmel_CG4022, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648307.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VSY1
      Related
      FBpp0076214
      Conserved Domains (1) summary
      cl00175
      Location:106 → 196
      alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VSY1 Q9VSY1

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