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    PLXNA4 plexin A4 [ Dromiciops gliroides (monito del monte) ]

    Gene ID: 122727928, updated on 22-Mar-2024

    Summary

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    Gene symbol
    PLXNA4
    Gene description
    plexin A4
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Dromiciops gliroides
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Microbiotheria; Microbiotheriidae; Dromiciops
    Orthologs
    human mouse all
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    Genomic context

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    See PLXNA4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    100 current mDroGli1.pri (GCF_019393635.1) 5 NC_057865.1 (113778457..114477692)

    Chromosome 5 - NC_057865.1Genomic Context describing neighboring genes Neighboring gene U6atac minor spliceosomal RNA Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 3 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC122727929 Neighboring gene cytochrome c oxidase subunit 6B1-like Neighboring gene podocalyxin like Neighboring gene muskelin 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_057865.1 Chromosome 5 Reference mDroGli1.pri

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables semaphorin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of axonogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of semaphorin receptor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plexin-A4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Dromiciops gliroides Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mDroGli1.pri

    Genomic

    1. NC_057865.1 Reference mDroGli1.pri

      Range
      113778457..114477692
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_043965884.1 → XP_043821819.1  plexin-A4

      Conserved Domains (8) summary
      cd11274
      Location:39 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      cd12790
      Location:1311 → 1888
      RasGAP_plexin_A; Ras-GTPase Activating Domain of type A plexins
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1142 → 1222
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1038
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1040 → 1140
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cl28922
      Location:1507 → 1600
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    2. XM_043965883.1 → XP_043821818.1  plexin-A4

      Conserved Domains (8) summary
      cd11274
      Location:39 → 510
      Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
      cd12790
      Location:1311 → 1888
      RasGAP_plexin_A; Ras-GTPase Activating Domain of type A plexins
      smart00423
      Location:509 → 547
      PSI; domain found in Plexins, Semaphorins and Integrins
      cd00603
      Location:1142 → 1222
      IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
      cd01179
      Location:954 → 1038
      IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01180
      Location:857 → 952
      IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cd01181
      Location:1040 → 1140
      IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
      cl28922
      Location:1507 → 1600
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    Nucleotide Protein
    Heading Accession and Version

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