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    EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 [ Gallus gallus (chicken) ]

    Gene ID: 395360, updated on 26-Nov-2024

    Summary

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    Official Symbol
    EIF2AK1provided by CGNC
    Official Full Name
    eukaryotic translation initiation factor 2 alpha kinase 1provided by CGNC
    Primary source
    CGNC:2470
    See related
    Ensembl:ENSGALG00010021765
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See EIF2AK1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 14 NC_052545.1 (971301..987262)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 14 NC_052586.1 (969957..985928)

    Chromosome 14 - NC_052545.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101751635 Neighboring gene lipopolysaccharide induced TNF factor Neighboring gene ubiquitin specific peptidase 42 Neighboring gene ankyrin repeat domain 61 Neighboring gene aminoacyl tRNA synthetase complex interacting multifunctional protein 2 Neighboring gene PMS1 homolog 2, mismatch repair system component

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Screening from a subtracted embryonic chick hindbrain cDNA library: identification of genes expressed during hindbrain, midbrain and cranial neural crest development. Christiansen JH, et al. Mech Dev, 2001 Apr. PMID 11287186
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    eukaryotic translation initiation factor 2-alpha kinase 1
    Names
    eukaryotic initiation factor 2 alpha kinase
    NP_989979.2
    XP_015149616.2
    XP_015149617.2
    XP_025010815.2
    XP_025010816.2
    XP_040503246.1
    XP_046783228.1
    XP_046783229.1
    XP_046783230.1
    XP_046783231.1
    XP_046783232.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204648.2 → NP_989979.2  eukaryotic translation initiation factor 2-alpha kinase 1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000257
      UniProtKB/TrEMBL
      Q98SS6
      Related
      ENSGALP00010031819.1, ENSGALT00010052913.1
      Conserved Domains (2) summary
      cd14049
      Location:152 → 588
      STKc_EIF2AK1_HRI; Catalytic domain of the Serine/Threonine kinase, eukaryotic translation Initiation Factor 2-Alpha Kinase 2 or Heme-Regulated Inhibitor kinase
      cl21453
      Location:158 → 347
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052545.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      971301..987262
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025155047.3 → XP_025010815.2  eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1

      UniProtKB/TrEMBL
      Q98SS6
      Conserved Domains (2) summary
      cd14049
      Location:152 → 588
      STKc_EIF2AK1_HRI; Catalytic domain of the Serine/Threonine kinase, eukaryotic translation Initiation Factor 2-Alpha Kinase 2 or Heme-Regulated Inhibitor kinase
      cl21453
      Location:158 → 347
      PKc_like; Protein Kinases, catalytic domain

    2. XM_015294130.4 → XP_015149616.2  eukaryotic translation initiation factor 2-alpha kinase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZKA2
      Related
      ENSGALP00010031820.1, ENSGALT00010052914.1
      Conserved Domains (2) summary
      cd14049
      Location:152 → 518
      STKc_EIF2AK1_HRI; Catalytic domain of the Serine/Threonine kinase, eukaryotic translation Initiation Factor 2-Alpha Kinase 2 or Heme-Regulated Inhibitor kinase
      cl21453
      Location:158 → 347
      PKc_like; Protein Kinases, catalytic domain

    3. XM_015294131.4 → XP_015149617.2  eukaryotic translation initiation factor 2-alpha kinase 1 isoform X5

      UniProtKB/TrEMBL
      Q98SS6
      Conserved Domains (2) summary
      cd14049
      Location:32 → 468
      STKc_EIF2AK1_HRI; Catalytic domain of the Serine/Threonine kinase, eukaryotic translation Initiation Factor 2-Alpha Kinase 2 or Heme-Regulated Inhibitor kinase
      cl21453
      Location:38 → 227
      PKc_like; Protein Kinases, catalytic domain

    4. XM_025155048.3 → XP_025010816.2  eukaryotic translation initiation factor 2-alpha kinase 1 isoform X2

      UniProtKB/TrEMBL
      Q98SS6
      Conserved Domains (2) summary
      cd14049
      Location:78 → 514
      STKc_EIF2AK1_HRI; Catalytic domain of the Serine/Threonine kinase, eukaryotic translation Initiation Factor 2-Alpha Kinase 2 or Heme-Regulated Inhibitor kinase
      cl21453
      Location:84 → 273
      PKc_like; Protein Kinases, catalytic domain

    5. XM_040647312.2 → XP_040503246.1  eukaryotic translation initiation factor 2-alpha kinase 1 isoform X3

      UniProtKB/TrEMBL
      Q98SS6
      Conserved Domains (2) summary
      cd14049
      Location:78 → 514
      STKc_EIF2AK1_HRI; Catalytic domain of the Serine/Threonine kinase, eukaryotic translation Initiation Factor 2-Alpha Kinase 2 or Heme-Regulated Inhibitor kinase
      cl21453
      Location:84 → 273
      PKc_like; Protein Kinases, catalytic domain

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052586.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      969957..985928
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046927272.1 → XP_046783228.1  eukaryotic translation initiation factor 2-alpha kinase 1 isoform X1

    2. XM_046927275.1 → XP_046783231.1  eukaryotic translation initiation factor 2-alpha kinase 1 isoform X4

    3. XM_046927276.1 → XP_046783232.1  eukaryotic translation initiation factor 2-alpha kinase 1 isoform X5

    4. XM_046927273.1 → XP_046783229.1  eukaryotic translation initiation factor 2-alpha kinase 1 isoform X2

    5. XM_046927274.1 → XP_046783230.1  eukaryotic translation initiation factor 2-alpha kinase 1 isoform X3

    Nucleotide Protein
    Heading Accession and Version

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