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    DGKA diacylglycerol kinase alpha [ Lagopus leucura (white-tailed ptarmigan) ]

    Gene ID: 122191473, updated on 18-Sep-2024

    Summary

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    Gene symbol
    DGKA
    Gene description
    diacylglycerol kinase alpha
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Lagopus leucura
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Tetraoninae; Lagopus
    Orthologs
    human mouse all
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    Genomic context

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    See DGKA in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    100 current USGS_WTPT01 (GCF_019238085.1) Unplaced Scaffold NW_024963999.1 (8638..15123)

    NW_024963999.1Genomic Context describing neighboring genes Neighboring gene tubulin alpha-1C chain Neighboring gene transmembrane protein 198-like Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene premelanosome protein Neighboring gene cyclin dependent kinase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_024963999 Unplaced Scaffold Reference USGS_WTPT01

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP-dependent diacylglycerol kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in diacylglycerol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    diacylglycerol kinase alpha

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Lagopus leucura Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference USGS_WTPT01

    Genomic

    1. NW_024963999.1 Reference USGS_WTPT01

      Range
      8638..15123
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042891744.1 → XP_042747678.1  diacylglycerol kinase alpha isoform X1

      Conserved Domains (4) summary
      smart00109
      Location:259 → 309
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00045
      Location:577 → 755
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:435 → 556
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00051
      Location:168 → 237
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    2. XM_042891745.1 → XP_042747679.1  diacylglycerol kinase alpha isoform X2

      Conserved Domains (4) summary
      smart00109
      Location:234 → 284
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00045
      Location:552 → 730
      DAGKa; Diacylglycerol kinase accessory domain (presumed)
      smart00046
      Location:410 → 531
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00051
      Location:143 → 212
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    3. XM_042891746.1 → XP_042747680.1  diacylglycerol kinase alpha isoform X3

      Conserved Domains (4) summary
      smart00109
      Location:259 → 309
      C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
      smart00046
      Location:435 → 556
      DAGKc; Diacylglycerol kinase catalytic domain (presumed)
      cd00051
      Location:168 → 237
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cl02440
      Location:577 → 739
      DAGK_acc; Diacylglycerol kinase accessory domain
    Nucleotide Protein
    Heading Accession and Version

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