U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    PTPN22 protein tyrosine phosphatase non-receptor type 22 [ Lagopus leucura (white-tailed ptarmigan) ]

    Gene ID: 122187076, updated on 22-Mar-2024

    Summary

    Go to the top of the page Help
    Gene symbol
    PTPN22
    Gene description
    protein tyrosine phosphatase non-receptor type 22
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Lagopus leucura
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Tetraoninae; Lagopus
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PTPN22 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    100 current USGS_WTPT01 (GCF_019238085.1) Unplaced Scaffold NW_024962290.1 (1551914..1565674)

    NW_024962290.1Genomic Context describing neighboring genes Neighboring gene adaptor related protein complex 4 subunit beta 1 Neighboring gene BCL2 like 15 Neighboring gene round spermatid basic protein 1 Neighboring gene putative homeodomain transcription factor 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NW_024962290 Unplaced Scaffold Reference USGS_WTPT01

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables non-membrane spanning protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in T cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in T cell receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of T cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of p38MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of tumor necrosis factor production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-tyrosine dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of CD8-positive, alpha-beta T cell proliferation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of defense response to virus by host IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of granzyme B production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of protein K63-linked ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of toll-like receptor 3 signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of toll-like receptor 4 signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of toll-like receptor 7 signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of toll-like receptor 9 signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of non-canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tyrosine-protein phosphatase non-receptor type 22

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Lagopus leucura Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference USGS_WTPT01

    Genomic

    1. NW_024962290.1 Reference USGS_WTPT01

      Range
      1551914..1565674
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042884311.1 → XP_042740245.1  tyrosine-protein phosphatase non-receptor type 22 isoform X1

      Conserved Domains (1) summary
      cd14602
      Location:57 → 290
      PTPc-N22; catalytic domain of tyrosine-protein phosphatase non-receptor type 22

    2. XM_042884312.1 → XP_042740246.1  tyrosine-protein phosphatase non-receptor type 22 isoform X2

      Conserved Domains (1) summary
      cd14602
      Location:57 → 290
      PTPc-N22; catalytic domain of tyrosine-protein phosphatase non-receptor type 22
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.