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    si:dkey-91m11.5 PH_BCR_vertebrate and RhoGAP_Bcr domain-containing protein [ Cheilinus undulatus (humphead wrasse) ]

    Gene ID: 121509609, updated on 22-Mar-2024

    Summary

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    Gene symbol
    si:dkey-91m11.5
    Gene description
    PH_BCR_vertebrate and RhoGAP_Bcr domain-containing protein
    See related
    EnsemblRapid:ENSCUDG00000020088
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cheilinus undulatus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Labriformes; Labridae; Cheilinus
    Orthologs
    zebrafish all
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    Genomic context

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    See si:dkey-91m11.5 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    25
    Annotation release Status Assembly LG Location
    100 current ASM1832078v1 (GCF_018320785.1) 5 NC_054869.1 (46551130..46618742, complement)

    Linkage Group 5 - NC_054869.1Genomic Context describing neighboring genes Neighboring gene adenosine A2a receptor a Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1-like a Neighboring gene intraflagellar transport 81 homolog Neighboring gene sarcoplasmic/endoplasmic reticulum calcium ATPase 2-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_054869.1 Chromosome 5 Reference ASM1832078v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PH_BCR_vertebrate and RhoGAP_Bcr domain-containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cheilinus undulatus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM1832078v1 Primary Assembly

    Genomic

    1. NC_054869.1 Reference ASM1832078v1 Primary Assembly

      Range
      46551130..46618742 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041787100.1 → XP_041643034.1  PH_BCR_vertebrate and RhoGAP_Bcr domain-containing protein

      Related
      ENSCUDP00000053614.1, ENSCUDT00000054404.1
      Conserved Domains (4) summary
      cd08686
      Location:937 → 1057
      C2_ABR; C2 domain in the Active BCR (Breakpoint cluster region) Related protein
      cd00160
      Location:524 → 714
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd04387
      Location:1076 → 1275
      RhoGAP_Bcr; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain, a Ser/Thr ...
      cl17171
      Location:709 → 901
      PH-like; Pleckstrin homology-like domain

    2. XM_041787099.1 → XP_041643033.1  PH_BCR_vertebrate and RhoGAP_Bcr domain-containing protein

      Conserved Domains (4) summary
      cd08686
      Location:937 → 1057
      C2_ABR; C2 domain in the Active BCR (Breakpoint cluster region) Related protein
      cd00160
      Location:524 → 714
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
      cd04387
      Location:1076 → 1275
      RhoGAP_Bcr; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain, a Ser/Thr ...
      cl17171
      Location:709 → 901
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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