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    tag-340 START domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175655, updated on 2-Nov-2024

    Summary

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    Official Symbol
    tag-340
    Official Full Name
    START domain-containing protein
    Primary source
    WormBase:WBGene00017826
    Locus tag
    CELE_F26F4.4
    See related
    AllianceGenome:WB:WBGene00017826
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lipid binding activity. Predicted to be involved in vesicle tethering to endoplasmic reticulum. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum-endosome membrane contact site and late endosome membrane. Predicted to colocalize with endoplasmic reticulum membrane. Orthologous to several human genes including STARD3 (StAR related lipid transfer domain containing 3). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See tag-340 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (4900508..4903170)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene RING-type E3 ubiquitin transferase Neighboring gene ncRNA Neighboring gene Mediator of RNA polymerase II transcription subunit 21 Neighboring gene C2H2-type domain-containing protein Neighboring gene Rhomboid-related protein 1 Neighboring gene ANK_REP_REGION domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in vesicle tethering to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    colocalizes_with endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum-endosome membrane contact site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in late endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    START domain-containing protein
    NP_001379724.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      4900508..4903170
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393331.1 → NP_001379724.1  START domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19819
      Conserved Domains (2) summary
      pfam01852
      Location:246 → 441
      START; START domain
      pfam10457
      Location:18 → 192
      MENTAL; Cholesterol-capturing domain
    Nucleotide Protein
    Heading Accession and Version

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