Baz1a bromodomain adjacent to zinc finger domain, 1A [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Baz1aprovided by RGD
Official Full Name: bromodomain adjacent to zinc finger domain, 1Aprovided by RGD
Primary source: RGD:1306199
See related: EnsemblRapid:ENSRNOG00000006828 AllianceGenome:RGD:1306199
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable DNA binding activity. Predicted to be involved in several processes, including nucleosome assembly; positive regulation of DNA replication; and regulation of gene expression. Predicted to be located in nucleus and pericentric heterochromatin. Predicted to be part of ACF complex and CHRAC. Predicted to be active in nuclear chromosome. Orthologous to human BAZ1A (bromodomain adjacent to zinc finger domain 1A). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 234.1), Spleen (RPKM 151.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 6q23

Exon count:: 30

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (78124872..78247672, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (72389701..72512516, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (75793223..75873854, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA-templated DNA replication	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
involved_in chromatin remodeling	ISO Inferred from Sequence Orthology more info
involved_in nucleosome assembly	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of DNA replication	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of DNA replication	ISO Inferred from Sequence Orthology more info
involved_in regulation of DNA replication	ISO Inferred from Sequence Orthology more info
involved_in regulation of DNA-templated transcription	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of heterochromatin formation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of ACF complex	ISO Inferred from Sequence Orthology more info
part_of CHRAC	IBA Inferred from Biological aspect of Ancestor more info
part_of CHRAC	ISO Inferred from Sequence Orthology more info
is_active_in nuclear chromosome	IBA Inferred from Biological aspect of Ancestor more info
located_in nuclear chromosome	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
located_in pericentric heterochromatin	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: bromodomain adjacent to zinc finger domain protein 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001170568.2 → NP_001164039.2 bromodomain adjacent to zinc finger domain protein 1A

Status: VALIDATED

Source sequence(s)

JAXUCZ010000006

UniProtKB/TrEMBL

F1M4U9

Related

ENSRNOP00000009080.7, ENSRNOT00000009080.9

Conserved Domains (7) summary

cd05504
Location:1419 → 1532

Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...

PTZ00121
Location:646 → 793

PTZ00121; MAEBL; Provisional

smart00571
Location:422 → 483

DDT; domain in different transcription and chromosome remodeling factors

cd15627
Location:1147 → 1192

PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)

pfam10537
Location:23 → 122

WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal

pfam15612
Location:590 → 635

WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1

pfam15613
Location:799 → 925

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086024.1 Reference GRCr8

Range

78124872..78247672 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063261906.1 → XP_063117976.1 bromodomain adjacent to zinc finger domain protein 1A isoform X2
XM_039112223.2 → XP_038968151.1 bromodomain adjacent to zinc finger domain protein 1A isoform X1

Conserved Domains (7) summary

cd05504
Location:1449 → 1562

Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...

PTZ00121
Location:646 → 793

PTZ00121; MAEBL; Provisional

smart00571
Location:422 → 483

DDT; domain in different transcription and chromosome remodeling factors

cd15627
Location:1177 → 1222

PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)

pfam10537
Location:23 → 122

WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal

pfam15612
Location:590 → 635

WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1

pfam15613
Location:799 → 925

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_063261908.1 → XP_063117978.1 bromodomain adjacent to zinc finger domain protein 1A isoform X3

UniProtKB/TrEMBL

A0A8I6G4X5
XM_063261907.1 → XP_063117977.1 bromodomain adjacent to zinc finger domain protein 1A isoform X3

UniProtKB/TrEMBL

A0A8I6G4X5

Related

ENSRNOP00000079177.1, ENSRNOT00000098593.2
XM_063261905.1 → XP_063117975.1 bromodomain adjacent to zinc finger domain protein 1A isoform X2
XM_039112222.2 → XP_038968150.1 bromodomain adjacent to zinc finger domain protein 1A isoform X1

Conserved Domains (7) summary

cd05504
Location:1449 → 1562

Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...

PTZ00121
Location:646 → 793

PTZ00121; MAEBL; Provisional

smart00571
Location:422 → 483

DDT; domain in different transcription and chromosome remodeling factors

cd15627
Location:1177 → 1222

PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)

pfam10537
Location:23 → 122

WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal

pfam15612
Location:590 → 635

WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1

pfam15613
Location:799 → 925

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_039112224.2 → XP_038968152.1 bromodomain adjacent to zinc finger domain protein 1A isoform X2

Conserved Domains (7) summary

cd05504
Location:1417 → 1530

Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...

PTZ00121
Location:614 → 761

PTZ00121; MAEBL; Provisional

smart00571
Location:422 → 483

DDT; domain in different transcription and chromosome remodeling factors

cd15627
Location:1145 → 1190

PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)

pfam10537
Location:23 → 122

WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal

pfam15612
Location:558 → 603

WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1

pfam15613
Location:767 → 893

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_039112225.2 → XP_038968153.1 bromodomain adjacent to zinc finger domain protein 1A isoform X3

UniProtKB/TrEMBL

A0A8I6G4X5

Conserved Domains (7) summary

cd05504
Location:1387 → 1500

Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...

PTZ00121
Location:614 → 761

PTZ00121; MAEBL; Provisional

smart00571
Location:422 → 483

DDT; domain in different transcription and chromosome remodeling factors

cd15627
Location:1115 → 1160

PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)

pfam10537
Location:23 → 122

WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal

pfam15612
Location:558 → 603

WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1

pfam15613
Location:767 → 893

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_063261904.1 → XP_063117974.1 bromodomain adjacent to zinc finger domain protein 1A isoform X2
XM_039112221.1 → XP_038968149.1 bromodomain adjacent to zinc finger domain protein 1A isoform X1

Conserved Domains (7) summary

cd05504
Location:1449 → 1562

Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...

PTZ00121
Location:646 → 793

PTZ00121; MAEBL; Provisional

smart00571
Location:422 → 483

DDT; domain in different transcription and chromosome remodeling factors

cd15627
Location:1177 → 1222

PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)

pfam10537
Location:23 → 122

WAC_Acf1_DNA_bd; ATP-utilising chromatin assembly and remodelling N-terminal

pfam15612
Location:590 → 635

WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1

pfam15613
Location:799 → 925

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_063261909.1 → XP_063117979.1 bromodomain adjacent to zinc finger domain protein 1A isoform X4
XM_039112227.2 → XP_038968155.1 bromodomain adjacent to zinc finger domain protein 1A isoform X6

UniProtKB/TrEMBL

A6HBL3

Conserved Domains (5) summary

cd05504
Location:933 → 1046

Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...

PTZ00121
Location:130 → 277

PTZ00121; MAEBL; Provisional

cd15627
Location:661 → 706

PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)

pfam15612
Location:74 → 119

WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1

pfam15613
Location:283 → 409

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif
XM_039112226.2 → XP_038968154.1 bromodomain adjacent to zinc finger domain protein 1A isoform X5

UniProtKB/TrEMBL

A6HBL3

Conserved Domains (5) summary

cd05504
Location:965 → 1078

Bromo_Acf1_like; Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) ...

PTZ00121
Location:162 → 309

PTZ00121; MAEBL; Provisional

cd15627
Location:693 → 738

PHD_BAZ1A; PHD finger found in bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)

pfam15612
Location:106 → 151

WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1

pfam15613
Location:315 → 441

WSD; Williams-Beuren syndrome DDT (WSD), D-TOX E motif