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    C44E4.5 NudC domain-containing protein 1 [ Caenorhabditis elegans ]

    Gene ID: 172067, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C44E4.5
    Official Full Name
    NudC domain-containing protein 1
    Primary source
    WormBase:WBGene00016654
    Locus tag
    CELE_C44E4.5
    See related
    AllianceGenome:WB:WBGene00016654
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in cytoplasm and nucleus. Orthologous to human NUDCD1 (NudC domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C44E4.5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003279.8 (4605655..4610221)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Ell-associated factor Eaf Neighboring gene Nucleic acid-binding, OB-fold protein Neighboring gene UBR-type domain-containing protein Neighboring gene ncRNA Neighboring gene Lupus La protein Neighboring gene Acyl-CoA-binding protein homolog 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans. Suen KM, et al. Nat Commun, 2020 Aug 25. PMID 32843637, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    NudC domain-containing protein 1
    NP_491406.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4605655..4610221
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059005.6 → NP_491406.2  NudC domain-containing protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491406.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A6PVA1
      Conserved Domains (1) summary
      cl00175
      Location:256 → 338
      alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
    Nucleotide Protein
    Heading Accession and Version

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