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    GEN1 GEN1 Holliday junction 5' flap endonuclease [ Manis javanica (Malayan pangolin) ]

    Gene ID: 108390682, updated on 14-Mar-2024

    Summary

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    Gene symbol
    GEN1
    Gene description
    GEN1 Holliday junction 5' flap endonuclease
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Manis javanica
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Pholidota; Manidae; Manis
    Orthologs
    human mouse all
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    Genomic context

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    See GEN1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    101 current YNU_ManJav_2.0 (GCF_014570535.1) Unplaced Scaffold NW_023436114.1 (12491124..12525586)
    100 previous assembly ManJav1.0 (GCF_001685135.1) Unplaced Scaffold NW_016528968.1 (258235..291466)

    NW_023436114.1Genomic Context describing neighboring genes Neighboring gene visinin like 1 Neighboring gene structural maintenance of chromosomes 6 Neighboring gene ubiquitin-conjugating enzyme E2 D3-like Neighboring gene mesogenin 1 Neighboring gene potassium voltage-gated channel modifier subfamily S member 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 5'-flap endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables four-way junction DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    flap endonuclease GEN homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Manis javanica Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference YNU_ManJav_2.0 Primary Assembly

    Genomic

    1. NW_023436114.1 Reference YNU_ManJav_2.0 Primary Assembly

      Range
      12491124..12525586
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017649892.2 → XP_017505381.2  flap endonuclease GEN homolog 1

      Conserved Domains (3) summary
      cd09905
      Location:195 → 338
      H3TH_GEN1; H3TH domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease
      cd09869
      Location:2 → 206
      PIN_GEN1; FEN-like PIN domains of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
      pfam18704
      Location:398 → 457
      Chromo_2; Chromatin organization modifier domain 2
    Nucleotide Protein
    Heading Accession and Version

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