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    LOC118542233 85/88 kDa calcium-independent phospholipase A2 [ Halichoerus grypus (gray seal) ]

    Gene ID: 118542233, updated on 25-Jan-2024

    Summary

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    Gene symbol
    LOC118542233
    Gene description
    85/88 kDa calcium-independent phospholipase A2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Halichoerus grypus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Halichoerus
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    Genomic context

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    See LOC118542233 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    100 current Tufts_HGry_1.1 (GCF_012393455.1) Unplaced Scaffold NW_023398963.1 (509145..593014, complement)

    NW_023398963.1Genomic Context describing neighboring genes Neighboring gene protein interacting with PRKCA 1 Neighboring gene solute carrier family 16 member 8 Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene uncharacterized LOC118542198 Neighboring gene MAF bZIP transcription factor F

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_023398963 Unplaced Scaffold Reference Tufts_HGry_1.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium-independent phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin crosslink formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament bundle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cardiolipin acyl-chain remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in plasma membrane organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ceramide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    85/88 kDa calcium-independent phospholipase A2; brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Halichoerus grypus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Tufts_HGry_1.1

    Genomic

    1. NW_023398963.1 Reference Tufts_HGry_1.1

      Range
      509145..593014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036102217.1 → XP_035958110.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      Conserved Domains (9) summary
      cd07212
      Location:480 → 758
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd07644
      Location:795 → 1009
      I-BAR_IMD_BAIAP2L2; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      cd11914
      Location:1114 → 1172
      SH3_BAIAP2L2; Src Homology 3 domain of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      PHA03307
      Location:1004 → 1267
      PHA03307; transcriptional regulator ICP4; Provisional
      COG0666
      Location:84 → 287
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:156 → 249
      Ank_2; Ankyrin repeats (3 copies)
      cd21762
      Location:1295 → 1298
      WH2; actin-binding sequence [structural motif]
      cl41728
      Location:1293 → 1308
      WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

    2. XM_036102218.1 → XP_035958111.1  85/88 kDa calcium-independent phospholipase A2 isoform X3

      Conserved Domains (9) summary
      cd07212
      Location:456 → 734
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd07644
      Location:771 → 985
      I-BAR_IMD_BAIAP2L2; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      cd11914
      Location:1090 → 1148
      SH3_BAIAP2L2; Src Homology 3 domain of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      PHA03307
      Location:980 → 1243
      PHA03307; transcriptional regulator ICP4; Provisional
      COG0666
      Location:116 → 317
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:316 → 344
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:186 → 279
      Ank_2; Ankyrin repeats (3 copies)
      cd21762
      Location:1271 → 1274
      WH2; actin-binding sequence [structural motif]
      cl41728
      Location:1269 → 1284
      WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

    3. XM_036102215.1 → XP_035958108.1  85/88 kDa calcium-independent phospholipase A2 isoform X1

      Conserved Domains (9) summary
      cd07212
      Location:510 → 788
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd07644
      Location:825 → 1039
      I-BAR_IMD_BAIAP2L2; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      cd11914
      Location:1144 → 1202
      SH3_BAIAP2L2; Src Homology 3 domain of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      PHA03307
      Location:1034 → 1297
      PHA03307; transcriptional regulator ICP4; Provisional
      COG0666
      Location:116 → 317
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:316 → 344
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:186 → 279
      Ank_2; Ankyrin repeats (3 copies)
      cd21762
      Location:1325 → 1328
      WH2; actin-binding sequence [structural motif]
      cl41728
      Location:1323 → 1338
      WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

    4. XM_036102216.1 → XP_035958109.1  85/88 kDa calcium-independent phospholipase A2 isoform X2

      Conserved Domains (9) summary
      cd07212
      Location:480 → 758
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd07644
      Location:795 → 1009
      I-BAR_IMD_BAIAP2L2; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      cd11914
      Location:1114 → 1172
      SH3_BAIAP2L2; Src Homology 3 domain of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      PHA03307
      Location:1004 → 1267
      PHA03307; transcriptional regulator ICP4; Provisional
      COG0666
      Location:84 → 287
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:286 → 314
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:156 → 249
      Ank_2; Ankyrin repeats (3 copies)
      cd21762
      Location:1295 → 1298
      WH2; actin-binding sequence [structural motif]
      cl41728
      Location:1293 → 1308
      WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

    5. XM_036102219.1 → XP_035958112.1  brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 isoform X4

      Conserved Domains (4) summary
      cd07212
      Location:32 → 310
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd07644
      Location:347 → 561
      I-BAR_IMD_BAIAP2L2; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      cd11914
      Location:666 → 724
      SH3_BAIAP2L2; Src Homology 3 domain of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      PHA03307
      Location:556 → 819
      PHA03307; transcriptional regulator ICP4; Provisional

    6. XM_036102220.1 → XP_035958113.1  brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 isoform X5

      Conserved Domains (4) summary
      cd07212
      Location:11 → 289
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd07644
      Location:326 → 540
      I-BAR_IMD_BAIAP2L2; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      cd11914
      Location:645 → 703
      SH3_BAIAP2L2; Src Homology 3 domain of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      PHA03307
      Location:535 → 798
      PHA03307; transcriptional regulator ICP4; Provisional

    7. XM_036102223.1 → XP_035958116.1  brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 isoform X8

      Conserved Domains (4) summary
      cd07644
      Location:223 → 437
      I-BAR_IMD_BAIAP2L2; Inverse (I)-BAR, also known as the IRSp53/MIM homology Domain (IMD), of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      cd11914
      Location:542 → 600
      SH3_BAIAP2L2; Src Homology 3 domain of Brain-specific Angiogenesis Inhibitor 1-Associated Protein 2-Like 2
      PHA03307
      Location:437 → 695
      PHA03307; transcriptional regulator ICP4; Provisional
      cl11396
      Location:9 → 186
      Patatin_and_cPLA2; Patatins and Phospholipases

    8. XM_036102222.1 → XP_035958115.1  85/88 kDa calcium-independent phospholipase A2 isoform X7

      Conserved Domains (4) summary
      cd07212
      Location:456 → 768
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      COG0666
      Location:114 → 317
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:316 → 344
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:186 → 279
      Ank_2; Ankyrin repeats (3 copies)

    9. XM_036102221.1 → XP_035958114.1  85/88 kDa calcium-independent phospholipase A2 isoform X6

      Conserved Domains (4) summary
      cd07212
      Location:510 → 822
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      COG0666
      Location:114 → 317
      ANKYR; Ankyrin repeat [Signal transduction mechanisms]
      sd00045
      Location:316 → 344
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:186 → 279
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
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