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    cacnb3b calcium channel, voltage-dependent, beta 3b [ Danio rerio (zebrafish) ]

    Gene ID: 559015, updated on 4-Jan-2025

    Summary

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    Official Symbol
    cacnb3bprovided by ZNC
    Official Full Name
    calcium channel, voltage-dependent, beta 3bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-090127-1
    See related
    Ensembl:ENSDARG00000076030 AllianceGenome:ZFIN:ZDB-GENE-090127-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to enable voltage-gated calcium channel activity. Predicted to act upstream of or within calcium ion transmembrane transport. Predicted to be part of voltage-gated calcium channel complex. Is expressed in nervous system and otic vesicle. Orthologous to human CACNB3 (calcium voltage-gated channel auxiliary subunit beta 3). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See cacnb3b in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (26936544..26962376)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (27009872..27035152)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene adenylate cyclase 6b Neighboring gene dentin sialophosphoprotein-like Neighboring gene Rho family GTPase 1b Neighboring gene deltex E3 ubiquitin ligase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Zebrafish as a Model to Unveil the Pro-Osteogenic Effects of Boron-Vitamin D3 Synergism. Sojan JM, et al. Front Nutr, 2022. PMID 35571926, Free PMC Article
    2. Identification and expression of voltage-gated calcium channel beta subunits in Zebrafish. Zhou W, et al. Dev Dyn, 2008 Dec. PMID 19035348
    3. RNA-seq transcriptomic analysis of adult zebrafish inner ear hair cells. Barta CL, et al. Sci Data, 2018 Feb 6. PMID 29406519, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables voltage-gated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of voltage-gated calcium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    voltage-dependent L-type calcium channel subunit beta-4
    Names
    CAB3b
    calcium channel, voltage-dependent, beta 3 subunit
    voltage-dependent calcium channel beta 3b subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      26936544..26962376
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021469989.2 → XP_021325664.1  voltage-dependent L-type calcium channel subunit beta-4

      UniProtKB/TrEMBL
      A0A8M9PL84
      Related
      ENSDARP00000100850.3, ENSDART00000115141.5
      Conserved Domains (3) summary
      pfam12052
      Location:16 → 56
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17036
      Location:56 → 123
      SH3; Src Homology 3 domain superfamily
      cl27059
      Location:172 → 349
      Guanylate_kin; Guanylate kinase

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395154.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      175628..207464
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_682310.8 → XP_687402.3  voltage-dependent L-type calcium channel subunit beta-4

      UniProtKB/TrEMBL
      A0A8M9PL84
      Conserved Domains (3) summary
      pfam12052
      Location:16 → 56
      VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
      cl17036
      Location:56 → 123
      SH3; Src Homology 3 domain superfamily
      cl27059
      Location:172 → 349
      Guanylate_kin; Guanylate kinase
    Nucleotide Protein
    Heading Accession and Version

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