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    Zfp867 zinc finger protein 867 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100125361, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp867provided by RGD
    Official Full Name
    zinc finger protein 867provided by RGD
    Primary source
    RGD:1642427
    See related
    EnsemblRapid:ENSRNOG00000022431 AllianceGenome:RGD:1642427
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF136 (zinc finger protein 136) and ZNF564 (zinc finger protein 564). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 45.3), Muscle (RPKM 35.7) and 9 other tissues See more
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    Genomic context

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    See Zfp867 in Genome Data Viewer
    Location:
    10q22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (44744355..44754764, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (44244813..44255223, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (45809121..45819530, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 47 Neighboring gene jumonji domain containing 4 Neighboring gene ferritin light chain 1 pseudogene Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8-like Neighboring gene ribosomal protein L18, pseudogene 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC156790

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC100125361
    Names
    zinc finger protein LOC100125361

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109677.2 → NP_001103147.2  uncharacterized protein LOC100125361

      See identical proteins and their annotated locations for NP_001103147.2

      Status: VALIDATED

      Source sequence(s)
      BC129129
      UniProtKB/TrEMBL
      A1L1M1
      Related
      ENSRNOP00000030432.4, ENSRNOT00000038951.5
      Conserved Domains (5) summary
      smart00349
      Location:4 → 44
      KRAB; krueppel associated box
      COG5048
      Location:139 → 299
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:199 → 219
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 43
      KRAB; KRAB box
      pfam13465
      Location:239 → 264
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      44744355..44754764 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268224.1 → XP_063124294.1  uncharacterized protein LOC100125361 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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