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    RTL6 retrotransposon Gag like 6 [ Homo sapiens (human) ]

    Gene ID: 84247, updated on 10-Dec-2024

    Summary

    Official Symbol
    RTL6provided by HGNC
    Official Full Name
    retrotransposon Gag like 6provided by HGNC
    Primary source
    HGNC:HGNC:13343
    See related
    Ensembl:ENSG00000188636 MIM:621006; AllianceGenome:HGNC:13343
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Mar6; Mart6; SIRH3; LDOC1L; dJ1033E15.2
    Expression
    Ubiquitous expression in brain (RPKM 18.2), ovary (RPKM 11.8) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See RTL6 in Genome Data Viewer
    Location:
    22q13.31
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (44492583..44498233, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (44976418..44982051, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (44888463..44894113, complement)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44839807-44840536 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44840537-44841266 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44843884-44844547 Neighboring gene long intergenic non-protein coding RNA 1656 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr22:44844727-44845926 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 19211 Neighboring gene MRPS18C pseudogene 6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44891229-44892006 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44892007-44892784 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13867 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13868 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:44923943-44924102 Neighboring gene uncharacterized LOC105373059 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44939408-44939962 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44939963-44940517 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44941073-44941626 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:44946331-44946858 Neighboring gene keratin 18 pseudogene 23

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    retrotransposon Gag-like protein 6
    Names
    LDOC1 like
    Sushi-Ichi retrotransposon homolog 3
    leucine zipper down-regulated in cancer 1 like
    leucine zipper protein down-regulated in cancer cells-like
    mammalian retrotransposon-derived 6
    mammalian retrotransposon-derived protein 6
    protein LDOC1L

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_032287.3NP_115663.2  retrotransposon Gag-like protein 6

      See identical proteins and their annotated locations for NP_115663.2

      Status: VALIDATED

      Source sequence(s)
      AL136553, BC018713, BC030232, Z75407
      Consensus CDS
      CCDS33662.1
      UniProtKB/Swiss-Prot
      Q6ICC9, Q6ZTR1
      UniProtKB/TrEMBL
      B4DKA7
      Related
      ENSP00000340434.3, ENST00000341255.4
      Conserved Domains (1) summary
      pfam16297
      Location:98177
      DUF4939; Domain of unknown function (DUF4939)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      44492583..44498233 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      44976418..44982051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)