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    MELK maternal embryonic leucine zipper kinase [ Cygnus atratus (black swan) ]

    Gene ID: 118258676, updated on 20-Mar-2024

    Summary

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    Gene symbol
    MELK
    Gene description
    maternal embryonic leucine zipper kinase
    See related
    EnsemblRapid:ENSACYG00000006489
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cygnus atratus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anserinae; Cygnus
    Orthologs
    human mouse all
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    Genomic context

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    See MELK in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2023_02 current CAtr_DNAZoo_HiC_assembly (GCF_013377495.2) Z NC_066396.1 (83772371..83794881)
    100 previous assembly Cygnus_atratus_primary_v1.0 (GCF_013377495.1) Unplaced Scaffold NW_023336705.1 (793240..815741)

    Chromosome Z - NC_066396.1Genomic Context describing neighboring genes Neighboring gene maternal embryonic leucine zipper kinase-like Neighboring gene endoplasmic reticulum aminopeptidase 1 Neighboring gene paired box 5 Neighboring gene zinc finger CCHC-type containing 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables tau-protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    maternal embryonic leucine zipper kinase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_013377495.2-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CAtr_DNAZoo_HiC_assembly Primary Assembly

    Genomic

    1. NC_066396.1 Reference CAtr_DNAZoo_HiC_assembly Primary Assembly

      Range
      83772371..83794881
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_035567611.2 → XP_035423504.1  maternal embryonic leucine zipper kinase isoform X2

      Conserved Domains (3) summary
      cd12198
      Location:561 → 655
      MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
      cd14341
      Location:283 → 334
      UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
      cd14078
      Location:9 → 265
      STKc_MELK; Catalytic domain of the Serine/Threonine Kinase, Maternal Embryonic Leucine zipper Kinase

    2. XM_035567609.2 → XP_035423502.1  maternal embryonic leucine zipper kinase isoform X1

      Conserved Domains (3) summary
      cd12198
      Location:562 → 656
      MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
      cd14341
      Location:283 → 334
      UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
      cd14078
      Location:9 → 265
      STKc_MELK; Catalytic domain of the Serine/Threonine Kinase, Maternal Embryonic Leucine zipper Kinase

    3. XM_035567614.2 → XP_035423507.1  maternal embryonic leucine zipper kinase isoform X3

      Related
      ENSACYP00000010567.1
      Conserved Domains (3) summary
      cd12198
      Location:498 → 592
      MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
      cd14341
      Location:219 → 270
      UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
      cl21453
      Location:9 → 201
      PKc_like; Protein Kinases, catalytic domain

    4. XM_035567610.2 → XP_035423503.1  maternal embryonic leucine zipper kinase isoform X1

      Related
      ENSACYP00000010589.1
      Conserved Domains (3) summary
      cd12198
      Location:562 → 656
      MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
      cd14341
      Location:283 → 334
      UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
      cd14078
      Location:9 → 265
      STKc_MELK; Catalytic domain of the Serine/Threonine Kinase, Maternal Embryonic Leucine zipper Kinase

    5. XM_035567613.2 → XP_035423506.1  maternal embryonic leucine zipper kinase isoform X2

      Conserved Domains (3) summary
      cd12198
      Location:561 → 655
      MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
      cd14341
      Location:283 → 334
      UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
      cd14078
      Location:9 → 265
      STKc_MELK; Catalytic domain of the Serine/Threonine Kinase, Maternal Embryonic Leucine zipper Kinase
    Nucleotide Protein
    Heading Accession and Version

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