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    SOCS5 suppressor of cytokine signaling 5 [ Cygnus atratus (black swan) ]

    Gene ID: 118254444, updated on 11-Apr-2024

    Summary

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    Gene symbol
    SOCS5
    Gene description
    suppressor of cytokine signaling 5
    See related
    EnsemblRapid:ENSACYG00000011378
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cygnus atratus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Anseriformes; Anatidae; Anserinae; Cygnus
    Orthologs
    human mouse all
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    Genomic context

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    See SOCS5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_02 current CAtr_DNAZoo_HiC_assembly (GCF_013377495.2) 3 NC_066364.1 (91989284..92018558, complement)
    100 previous assembly Cygnus_atratus_primary_v1.0 (GCF_013377495.1) Unplaced Scaffold NW_023336588.1 (15946213..15980487)

    Chromosome 3 - NC_066364.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118256343 Neighboring gene uncharacterized LOC118256337 Neighboring gene CXXC repeat containing interactor of PDZ3 domain Neighboring gene phosphatidylinositol glycan anchor biosynthesis class F Neighboring gene ras homolog family member Q

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway via JAK-STAT IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in epidermal growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of phosphatidylinositol 3-kinase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    suppressor of cytokine signaling 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_013377495.2-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CAtr_DNAZoo_HiC_assembly Primary Assembly

    Genomic

    1. NC_066364.1 Reference CAtr_DNAZoo_HiC_assembly Primary Assembly

      Range
      91989284..92018558 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_035559674.2 → XP_035415567.1  suppressor of cytokine signaling 5

      Related
      ENSACYP00000018576.1
      Conserved Domains (3) summary
      cd03739
      Location:479 → 535
      SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
      pfam12610
      Location:146 → 195
      SOCS; Suppressor of cytokine signalling
      cl15255
      Location:370 → 470
      SH2; Src homology 2 (SH2) domain

    2. XM_050710117.1 → XP_050566074.1  suppressor of cytokine signaling 5

    3. XM_035559665.2 → XP_035415558.1  suppressor of cytokine signaling 5

      Conserved Domains (3) summary
      cd03739
      Location:479 → 535
      SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
      pfam12610
      Location:146 → 195
      SOCS; Suppressor of cytokine signalling
      cl15255
      Location:370 → 470
      SH2; Src homology 2 (SH2) domain

    4. XM_035559682.2 → XP_035415575.1  suppressor of cytokine signaling 5

      Related
      ENSACYP00000018596.1
      Conserved Domains (3) summary
      cd03739
      Location:479 → 535
      SOCS_SOCS5; SOCS (suppressors of cytokine signaling) box of SOCS5-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS5 inhibits Th2 differentiation by inhibiting ...
      pfam12610
      Location:146 → 195
      SOCS; Suppressor of cytokine signalling
      cl15255
      Location:370 → 470
      SH2; Src homology 2 (SH2) domain
    Nucleotide Protein
    Heading Accession and Version

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