asb13a.2 ankyrin repeat and SOCS box containing 13a, tandem duplicate 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: asb13a.2provided by ZNC
Official Full Name: ankyrin repeat and SOCS box containing 13a, tandem duplicate 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-041210-88
See related: Ensembl:ENSDARG00000045765 AllianceGenome:ZFIN:ZDB-GENE-041210-88
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkey-108d22.2
Summary: Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within intracellular signal transduction. Orthologous to human ASB13 (ankyrin repeat and SOCS box containing 13). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 4

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (11483361..11524888)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (11484361..11526039)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within intracellular signal transduction	IEA Inferred from Electronic Annotation more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein LOC563551

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001126110.1 → NP_001119582.1 uncharacterized protein LOC563551

See identical proteins and their annotated locations for NP_001119582.1

Status: PREDICTED

Source sequence(s)

BX469931

UniProtKB/TrEMBL

A0A8N7UYY1, Q1LX92

Related

ENSDARP00000112991.1, ENSDART00000140954.2

Conserved Domains (5) summary

cd00204
Location:46 → 172

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

cd03729
Location:239 → 280

SOCS_ASB13; SOCS (suppressors of cytokine signaling) box of ASB13-like proteins. ASB family members have a C-terminal SOCS box and an N-terminal ankyrin-related sequence. The general function of the SOCS box is the recruitment of the ubiquitin-transferase system. ...

pfam12796
Location:123 → 214

Ank_2; Ankyrin repeats (3 copies)

pfam13637
Location:19 → 72

Ank_4; Ankyrin repeats (many copies)

sd00045
Location:20 → 49

ANK; ANK repeat [structural motif]