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    Apoa2 apolipoprotein A2 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101701317, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Apoa2
    Gene description
    apolipoprotein A2
    Locus tag
    GW7_00499
    See related
    Ensembl:ENSHGLG00000018928
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    See Apoa2 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624794.1 (164351..165676)

    NW_004624794.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L12 pseudogene Neighboring gene nuclear receptor subfamily 1 group I member 3 Neighboring gene translocase of outer mitochondrial membrane 40 like Neighboring gene Fc fragment of IgE receptor Ig Neighboring gene NADH:ubiquinone oxidoreductase core subunit S2 Neighboring gene protein FAM92A pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624794 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables apolipoprotein receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cholesterol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables high-density lipoprotein particle binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables high-density lipoprotein particle receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phosphatidylcholine binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cholesterol metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cholesterol transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in high-density lipoprotein particle assembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in high-density lipoprotein particle remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipoprotein metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in low-density lipoprotein particle remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of lipase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in triglyceride-rich lipoprotein particle remodeling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in blood microparticle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of chylomicron IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of spherical high-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of very-low-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    apolipoprotein A-II
    Names
    apolipoprotein A-II preproprotein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624794.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      164351..165676
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004858661.2 → XP_004858718.1  apolipoprotein A-II

      See identical proteins and their annotated locations for XP_004858718.1

      UniProtKB/Swiss-Prot
      G5BWH8
      Related
      ENSHGLP00000026611.1, ENSHGLT00000026848.1
      Conserved Domains (1) summary
      pfam04711
      Location:24 → 98
      ApoA-II; Apolipoprotein A-II (ApoA-II)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G5BWH8.1 GenPept UniProtKB/Swiss-Prot:G5BWH8

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