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    MAP18 microtubule-associated protein 18 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834489, updated on 18-Sep-2024

    Summary

    Official Symbol
    MAP18
    Official Full Name
    microtubule-associated protein 18
    Primary source
    TAIR:AT5G44610
    Locus tag
    AT5G44610
    See related
    Araport:AT5G44610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    K15C23.5; K15C23_5; microtubule-associated protein 18; PCAP2; PLASMA MEMBRANE ASSOCIATED CA2+-BINDING PROTEIN-2
    Summary
    Encodes a protein with seven repeated VEEKK motifs. RNAi and overexpression experiments suggest that the gene is not involved in cell division but might be consequential for cell shape of epidermal and cortical cells. The protein encoded by this gene binds to cortical microtubules and inhibits tubulin polymerization. Associates to the plasma membrane and interacts with calmodulin and phosphatidylinositol phosphates, indicating an involvement in cellular signal transduction. Expression is enhanced by abiotic and hormonal factors. Induced during senescence.
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    Genomic context

    See MAP18 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (17993535..17994722, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene cytochrome P450, family 706, subfamily A, polypeptide 3 Neighboring gene Terpenoid cyclases/Protein prenyltransferases superfamily protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    NM_001344568.1
    NM_001344569.1
    NM_123828.4

    Gene Ontology Provided by TAIR

    Component Evidence Code Pubs
    colocalizes_with cortical microtubule PubMed 
    located_in plasma membrane PubMed 
    located_in plasma membrane PubMed 
    located_in pollen tube PubMed 

    General protein information

    Preferred Names
    microtubule-associated protein 18
    NP_568636.1
    • microtubule-associated protein 18 (MAP18); FUNCTIONS IN: microtubule binding, calmodulin binding, phosphatidylinositol binding; INVOLVED IN: in 9 processes; LOCATED IN: cortical microtubule, plasma membrane; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis; CONTAINS InterPro DOMAIN/s: DREPP plasma membrane polypeptide (InterPro:IPR008469); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17993535..17994722 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123828.4 → NP_568636.1  microtubule-associated protein 18 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568636.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z2P4, Q9LU05
      UniProtKB/TrEMBL
      A0A178UQA7, A0A5S9YB01
    2. NM_001344568.1 → NP_001331522.1  microtubule-associated protein 18 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z2P4, Q9LU05
      UniProtKB/TrEMBL
      A0A178UQA7, A0A5S9YB01
    3. NM_001344569.1 → NP_001331521.1  microtubule-associated protein 18 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C0Z2P4, Q9LU05
      UniProtKB/TrEMBL
      A0A178UQA7, A0A5S9YB01
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