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    TOPP6 type one serine/threonine protein phosphatase 6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834356, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TOPP6
    Official Full Name
    type one serine/threonine protein phosphatase 6
    Primary source
    TAIR:AT5G43380
    Locus tag
    AT5G43380
    See related
    Araport:AT5G43380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    type one serine/threonine protein phosphatase 6
    Summary
    encodes a type I serine/threonine protein phosphatase expressed in expressed in roots, rosettes and flowers.
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    Genomic context

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    See TOPP6 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    4
    Sequence:
    Chromosome: 5; NC_003076.8 (17419790..17421982, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene phosphate transporter 1;3 Neighboring gene phosphate transporter 2 Neighboring gene plant/protein Neighboring gene plant/protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular cloning and chromosomal mapping of type one serine/threonine protein phosphatases in Arabidopsis thaliana. Lin Q, et al. Plant Mol Biol, 1998 Jun. PMID 9617814
    2. Identification and functional characterization of inhibitor-3, a regulatory subunit of protein phosphatase 1 in plants. Takemiya A, et al. Plant Physiol, 2009 May. PMID 19329567, Free PMC Article
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036923.1
    NM_123704.3
    NM_180792.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein dephosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    type one serine/threonine protein phosphatase 6
    NP_001032000.1
    • type one serine/threonine protein phosphatase 6 (TOPP6); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: type one serine/threonine protein phosphatase 4 (TAIR:AT2G39840.1); Has 7210 Blast hits to 7010 proteins in 618 species: Archae - 78; Bacteria - 522; Metazoa - 2407; Fungi - 1451; Plants - 977; Viruses - 15; Other Eukaryotes - 1760 (source: NCBI BLink).
    NP_568625.1
    • type one serine/threonine protein phosphatase 6 (TOPP6); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: type one serine/threonine protein phosphatase 4 (TAIR:AT2G39840.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_851123.1
    • type one serine/threonine protein phosphatase 6 (TOPP6); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: type one serine/threonine protein phosphatase 4 (TAIR:AT2G39840.1); Has 7151 Blast hits to 6957 proteins in 613 species: Archae - 78; Bacteria - 520; Metazoa - 2406; Fungi - 1417; Plants - 983; Viruses - 15; Other Eukaryotes - 1732 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      17419790..17421982 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180792.3 → NP_851123.1  type one serine/threonine protein phosphatase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851123.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48641, O82733, Q2V319, Q8L761
      UniProtKB/TrEMBL
      A0A5S9YAM6
      Conserved Domains (2) summary
      PTZ00480
      Location:6 → 297
      PTZ00480; serine/threonine-protein phosphatase; Provisional
      cd07414
      Location:6 → 293
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain

    2. NM_123704.3 → NP_568625.1  type one serine/threonine protein phosphatase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568625.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178URQ1
      Conserved Domains (2) summary
      PTZ00480
      Location:6 → 297
      PTZ00480; serine/threonine-protein phosphatase; Provisional
      cd07414
      Location:6 → 293
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain

    3. NM_001036923.1 → NP_001032000.1  type one serine/threonine protein phosphatase 6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001032000.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178URQ1
      Conserved Domains (2) summary
      PTZ00480
      Location:6 → 297
      PTZ00480; serine/threonine-protein phosphatase; Provisional
      cd07414
      Location:6 → 293
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82733.3

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