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    UBC1 ubiquitin carrier protein 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838002, updated on 18-Sep-2024

    Summary

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    Official Symbol
    UBC1
    Official Full Name
    ubiquitin carrier protein 1
    Primary source
    TAIR:AT1G14400
    Locus tag
    AT1G14400
    See related
    Araport:AT1G14400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATUBC1; F14L17.17; F14L17_17; ubiquitin carrier protein 1; UBIQUITIN CARRIER PROTEIN 1; UBIQUITIN CONJUGATING ENZYME 1
    Summary
    ubiquitin carrier protein
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    Genomic context

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    See UBC1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (4926486..4928812, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein kinase 2A Neighboring gene IQ-domain 28 Neighboring gene ncRNA Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene ssDNA-binding transcriptional regulator Neighboring gene Pectate lyase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. E2 conjugases UBC1 and UBC2 regulate MYB42-mediated SOS pathway in response to salt stress in Arabidopsis. Sun Y, et al. New Phytol, 2020 Jul. PMID 32167578
    2. Repression of the floral transition via histone H2B monoubiquitination. Gu X, et al. Plant J, 2009 Feb. PMID 18980658
    3. The E2 ubiquitin-conjugating enzymes, AtUBC1 and AtUBC2, play redundant roles and are involved in activation of FLC expression and repression of flowering in Arabidopsis thaliana. Xu L, et al. Plant J, 2009 Jan. PMID 18798874
    4. Effect of Arabidopsis COP10 ubiquitin E2 enhancement activity across E2 families and functional conservation among its canonical homologues. Lau OS, et al. Biochem J, 2009 Mar 15. PMID 19061479
    5. Histone H2B monoubiquitination in the chromatin of FLOWERING LOCUS C regulates flowering time in Arabidopsis. Cao Y, et al. Plant Cell, 2008 Oct. PMID 18849490, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. E2 conjugases UBC1 and UBC2 regulate MYB42-mediated SOS pathway in response to salt stress in Arabidopsis.
      Title: E2 conjugases UBC1 and UBC2 regulate MYB42-mediated SOS pathway in response to salt stress in Arabidopsis.
    2. UBC1 and UBC2 redundantly mediate H2B monoubiquitination, and upregulate the expression of FLC.
      Title: Repression of the floral transition via histone H2B monoubiquitination.
    3. The double mutant Atubc1-1 Atubc2-1 shows a dramatically enhanced mutant phenotype. These two genes act together with HUB1/HUB2 in H2B ubiquitylation, which is involved in the activation of floral repressor genes.
      Title: The E2 ubiquitin-conjugating enzymes, AtUBC1 and AtUBC2, play redundant roles and are involved in activation of FLC expression and repression of flowering in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101307.5
    NM_202096.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables histone H2B deubiquitinase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables ubiquitin conjugating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within leaf morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of flower development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within vegetative to reproductive phase transition of meristem IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin carrier protein 1
    NP_563951.1
    • ubiquitin carrier protein 1 (UBC1); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquiting-conjugating enzyme 2 (TAIR:AT2G02760.1); Has 10640 Blast hits to 10586 proteins in 402 species: Archae - 0; Bacteria - 2; Metazoa - 4553; Fungi - 2331; Plants - 2017; Viruses - 26; Other Eukaryotes - 1711 (source: NCBI BLink).
    NP_973825.1
    • ubiquitin carrier protein 1 (UBC1); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquiting-conjugating enzyme 2 (TAIR:AT2G02760.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      4926486..4928812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101307.5 → NP_563951.1  ubiquitin carrier protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563951.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25865, Q4TZ08
      UniProtKB/TrEMBL
      A0A178WMI7, A0A5S9UFE9
      Conserved Domains (1) summary
      pfam00179
      Location:8 → 145
      UQ_con; Ubiquitin-conjugating enzyme

    2. NM_202096.2 → NP_973825.1  ubiquitin carrier protein 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973825.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P25865, Q4TZ08
      UniProtKB/TrEMBL
      A0A178WMI7, A0A5S9UFE9
      Conserved Domains (1) summary
      pfam00179
      Location:8 → 145
      UQ_con; Ubiquitin-conjugating enzyme
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P25865.1

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